Magnesium Injection Ensures Analgesia and Steroid Avoidance During Vaccination, Viremia or Immunocompromise
Overview
- Phase
- Not Applicable
- Intervention
- Magnesium
- Conditions
- Steroid Metabolism Disorder
- Sponsor
- Salem Anaesthesia Pain Clinic
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- Pain score, objective measurement using the validated Numeric Pain Rating scale
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
Steroid injections are used for interventional pain management. However, their side-effect of immunosuppression may increase the risk of infections. Magnesium is an alternative anti-nociceptive injection that may be used instead of steroids.
Prospective observational study of patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using the numeric pain rating scale. Sleep score is measured using the Likert sleep scale. A change in the pain or sleep scores by 2-points is considered significant.
Detailed Description
Corticosteroid injections are used for interventional pain management. The immunosuppression effect of steroid injection may increase the risk of infections. Magnesium is an alternative anti-nociceptive agent that may be used for interventional pain injection therapy, instead of steroids. Prospective observational clinical study of pain clinic patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using the numeric pain rating scale. Sleep score is measured using the Likert sleep scale. A change in the pain or sleep scores by 2-points is considered significant. Data analyzed with IBM® SPSS® Statistics 25 (IBM Corp, Armonk, NY); using Student's t-test, ANOVA, Pearson Chi-square test, and regression analysis. P-value \<0.05 is considered significant.
Investigators
Eligibility Criteria
Inclusion Criteria
- •adult chronic pain patients
- •previous interventional injection therapy
- •consent for interventional injection therapy
- •good treatment compliance
- •regular sleep diary
- •regular pain diary
- •informed consent for diary review
- •consent for clinical record quality assurance review
Exclusion Criteria
- •organ insufficiency
- •cognitive disorder
- •inability to provide consent
- •major neuropsychiatric disorder
- •unreliable diary
- •poor treatment compliance
- •previous adverse/allergic reactions to magnesium
Arms & Interventions
Adult chronic pain patients
Cohort of adult chronic pain patients, undergoing interventional injection therapy for pain management at a Canadian pain clinic
Intervention: Magnesium
Outcomes
Primary Outcomes
Pain score, objective measurement using the validated Numeric Pain Rating scale
Time Frame: 12 weeks
Pain score, using the Numeric Pain Rating scale of 0 to 10, low scores indicate less pain, high scores indicate worse pain
Secondary Outcomes
- Sleep quality score, objective measurement using the validated Likert sleep scale(12 weeks)