Magnesium Injection Ensures Analgesia and Steroid Avoidance During Vaccination, Viremia or Immunocompromise
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Pain score, objective measurement using the validated Numeric Pain Rating scale
研究概览
简要总结
Steroid injections are used for interventional pain management. However, their side-effect of immunosuppression may increase the risk of infections. Magnesium is an alternative anti-nociceptive injection that may be used instead of steroids.
Prospective observational study of patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using the numeric pain rating scale. Sleep score is measured using the Likert sleep scale. A change in the pain or sleep scores by 2-points is considered significant.
详细描述
Corticosteroid injections are used for interventional pain management. The immunosuppression effect of steroid injection may increase the risk of infections. Magnesium is an alternative anti-nociceptive agent that may be used for interventional pain injection therapy, instead of steroids.
Prospective observational clinical study of pain clinic patients who received magnesium injection for interventional pain therapy, instead of steroid injection. Post-injection data collection includes numerical rating pain score, and sleep quality score. Pain is measured using the numeric pain rating scale. Sleep score is measured using the Likert sleep scale. A change in the pain or sleep scores by 2-points is considered significant. Data analyzed with IBM® SPSS® Statistics 25 (IBM Corp, Armonk, NY); using Student's t-test, ANOVA, Pearson Chi-square test, and regression analysis. P-value <0.05 is considered significant.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •adult chronic pain patients
- •previous interventional injection therapy
- •consent for interventional injection therapy
- •good treatment compliance
- •regular sleep diary
- •regular pain diary
- •informed consent for diary review
- •consent for clinical record quality assurance review
排除标准
- •organ insufficiency
- •cognitive disorder
- •inability to provide consent
- •major neuropsychiatric disorder
- •unreliable diary
- •poor treatment compliance
- •previous adverse/allergic reactions to magnesium
研究组 & 干预措施
Adult chronic pain patients
Cohort of adult chronic pain patients, undergoing interventional injection therapy for pain management at a Canadian pain clinic
干预措施: Magnesium (Drug)
结局指标
主要结局
Pain score, objective measurement using the validated Numeric Pain Rating scale
时间窗: 12 weeks
Pain score, using the Numeric Pain Rating scale of 0 to 10, low scores indicate less pain, high scores indicate worse pain
次要结局
- Sleep quality score, objective measurement using the validated Likert sleep scale(12 weeks)