Effect of Prewarming During Induction of General Anesthesia Combined With Warmed Intravenous Fluid on Core Temperature.

Not Applicable

Completed

• Conditions: Urologic Diseases
• Interventions: Procedure: warming during induction of anesthesia; Procedure: Prewarmed intravenous fluid administration

• Registration Number: NCT05636189
• Lead Sponsor: Inje University

Brief Summary

Hypothermia occurs frequently during general anesthesia. This study is to evaluate the efficacy of 10 minutes of prewarming during induction of general anesthesia during urologic surgery.

Detailed Description

Hypothermia is of continuous issue in patients undergoing general anesthesia. During urologic operation (transurethral resection of bladder and prostate), bladder irrigation worsens hypothermia. Hence, various methods including prewarming of the patient are used to maintain core temperature during operation.

Prewarming is found to be effective in maintaining core temperature perioperatively by increasing peripheral tissue heat content. However, applying more than 30 minutes of prewarming may be impractical as a clinical routine practice. Hence, developing simple and effective method to prevent hypothermia is expected.

Here, the investigators planned to examine the effect of active warming (10 minutes of warming during induction of general anesthesia and prewarmed intravenous fluid intraoperatively) on hypothermia in patients undergoing urologic operation under general anesthesia.

Study Timeline

• Study Start: 2022-11-01
• Study First Submitted: 2022-11-23
• Study First Submitted QC: 2022-11-23
• Study First Posted: 2022-12-05
• Status Verified: 2023-08
• Primary Completion: 2023-08-08
• Study Completion: 2023-08-08
• Last Update Submitted: 2023-08-29
• Last Update Posted: 2023-08-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• patients undergoing urologic surgery(transurethral resection of bladder, prostate)

Exclusion Criteria

• moderate to severe cardiopulmonary, renal impairment
• previous thyroid disease
• any infection sign
• abnormal temperature prior to induction of general anesthesia (<36'C or >37.5'C)
• refusal to participate in the study
• unable to understand the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
warming group	Prewarmed intravenous fluid administration	warming of the patient with whole body warming blanket in the OR during induction of anesthesia, prewarmed intravenous fluid during the operation.
warming group	warming during induction of anesthesia	warming of the patient with whole body warming blanket in the OR during induction of anesthesia, prewarmed intravenous fluid during the operation.

Primary Outcome Measures

Name	Time	Method
incidence of hypothermia at the end of the operation	approximately 1-2hours after induction (at the end of operation)	number of patients with hypothermia (\<36'C) using esophageal stethoscope will be recorded.

Secondary Outcome Measures

Name	Time	Method
change in temperature drop before and end of operation	on arrival at the OR upto 1-2hours after induction (at the end of the operation)	change in core temperature will be observed
incidence of shivering	upto 1 hour after end of the operation (on arrival at the postanesthesia care unit)	4 point shivering scale (0=none, 1=core and neck shivering, 2= upper extremity 3= whole body) will be used.
thermal comfort	upto 1hour after end of the operation (at discharge of postanesthesia care unit)	thermal comfort scale ( 0= very cold, 5= fine, 10= very hot and uncomfortable) will be used.

Trial Locations

Locations (1)

Sanggye paik hospital; 🇰🇷 Seoul, Korea, Republic of