Study on the Effect of Fish Oil and Appetite
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Appetite and satiation
研究概览
简要总结
20 normal-weight healthy subjects (10 males, 10 females) were in two periods given 10 of 0.5-mL capsules/day of fish oil and soybean oil for 3 weeks. In the end of each period they were given a standard breakfast and asked to report their appetite on visual analogue scales (VAS) immediately before and after the meal. The results were analyzed in accordance with the paired design under consideration of both supplement sequence and gender.
详细描述
In a randomized cross-over design, 20 normal-weight healthy subjects (10 males, 10 females) were given 10 of 0.5-mL capsules/day of fish oil and soybean oil for 3 weeks. In the end of each period they were given a standard breakfast and asked to report their appetite on visual analogue scales (VAS) immediately before and after the meal. The results were analyzed in accordance with the paired design under consideration of both supplement sequence and gender.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Normal weight (18.5<BMI<25 kg/m2).
排除标准
- •Subjects taking medication that could influence appetite.
- •Subjects with special nutritional needs e.g. pregnant and lactating, seriously ill or old people.
- •Subjects that had had fish oil-supplements for four weeks prior to the intervention period.
研究组 & 干预措施
Soy bean oil
5 g/d in 10 capsules
干预措施: Fish oil (Dietary Supplement)
Fish oil
5 g/d in 10 capsules, providing 3.5 g of long-chain n-3 fatty acids
干预措施: Fish oil (Dietary Supplement)
结局指标
主要结局
Appetite and satiation
时间窗: October 7th - November 25th 2011
Appetite and satiation were measured by visual analogue scales (VAS), which assessed satiation, hunger, fullness and desire to eat. Each scale was 100 mm in length with words anchored at each end, expressing the most positive and negative rating of each category.
次要结局
- Weight change(October 7th - November 25th 2011)
研究者
AAstrup
Associate Professore Lotte Lauritzen
University of Copenhagen