Changes in Cardiovascular Hemodynamics During Peritoneal Dialysis
Not Applicable
Terminated
- Conditions
- Peritoneal Dialysis
- Registration Number
- NCT00119990
- Lead Sponsor
- University of Aarhus
- Brief Summary
During peritoneal dialysis, water is removed from the body. This sometimes occurs at rates of up to 500 ml/h. During shifts with dialysate with high glucose content, an increase in blood pressure has been described. The effect upon central hemodynamics is unknown. The researchers are investigating the effects of low and high glucose dialysate and icodextrin on cardiac output, stroke volume, pulse rate and blood pressure. The researchers have hypothesized that the effects seen are induced by vasopressin.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
- Peritoneal dialysis patients
Read More
Exclusion Criteria
- Insulin dependent diabetes mellitus
- AV-fistula, cardial arrhythmia persistence, or severe cardiac and lung disease
- Recent infectious disease
- Severe psychiatric disease
- Hypersensitivity to icodextrin
Read More
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Changes in cardiac hemodynamics. (Cardiac Output, stroke volume, pulse rate, blood pressure and total peripheral resistance) 4 hours
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Deparment of Renal Medicine, Skejby Hospital
🇩🇰Aarhus, Denmark
Deparment of Renal Medicine, Skejby Hospital🇩🇰Aarhus, Denmark