Changes in Cardiovascular Hemodynamics During Peritoneal Dialysis; the Effect of Different Dialysates

University of Aarhus1 site in 1 country15 target enrollmentJanuary 2006

ConditionsPeritoneal Dialysis

DrugsIcodextrin (dialysate)Physioneal (dialysate) 1.36% and 2.27%

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Peritoneal Dialysis
Sponsor: University of Aarhus
Enrollment: 15
Locations: 1
Primary Endpoint: Changes in cardiac hemodynamics. (Cardiac Output, stroke volume, pulse rate, blood pressure and total peripheral resistance)
Status: Terminated
Last Updated: 17 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

During peritoneal dialysis, water is removed from the body. This sometimes occurs at rates of up to 500 ml/h. During shifts with dialysate with high glucose content, an increase in blood pressure has been described. The effect upon central hemodynamics is unknown. The researchers are investigating the effects of low and high glucose dialysate and icodextrin on cardiac output, stroke volume, pulse rate and blood pressure. The researchers have hypothesized that the effects seen are induced by vasopressin.

Registry

clinicaltrials.gov

Start Date

January 2006

End Date

January 2010

Last Updated

17 years ago

Study Type

Interventional

Study Design

Crossover