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临床试验/CTRI/2025/07/091725
CTRI/2025/07/091725
尚未招募
不适用

EFFICACY OF PREEMPTIVE ULTRASOUND - GUIDED MODIFIED THORACOABDOMINAL NERVE BLOCK THROUGH PERICHONDRIAL APPROACH (M -TAPA) FOR POSTOPERATIVE ANALGESIA IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY UNDER GENERAL ANAESTHESIA.

Dr Rekha S1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2025年8月4日最近更新:

概览

阶段
不适用
状态
尚未招募
发起方
Dr Rekha S
入组人数
45
试验地点
1
主要终点
To assess the duration of postoperative analgesia following laparoscopic cholecystectomy

概览

简要总结

Laparoscopic cholecystectomy brings benefits such as less pain, shorter hospital stay, and earlier recovery, and it is a cost-effective procedure. Though it is known for its minimally invasive nature, postoperative pain management remains challenging. Poorly controlled early postoperative pain impairs the quality of recovery, increasing the risk of postoperative pulmonary complications. It was observed that the abdominal pain following Laparoscopic cholecystectomy mostly originates from the incision area, and the remaining part consists of visceral and referred pain. Among various regional techniques, the subcostal transversus abdominis plane block  is a regional analgesic technique that can provide analgesia of the supraumbilical abdomen and has showed greatest reduction in pain score at 12hours postoperatively compared with other regional analgesic techniques. Modified Thoracoabdominal nerve block through perichondrial approach, which administers local anaesthetics only between the costal cartilage and the transverse abdominis muscle which provides wide blockage area that includes T5 and T11 to T12 dermatomal levels because the applied local anaesthetics also passes the linea semilunaris. It also has an advantage of performing the block in supine position

In this background the research question of the present study is to assess the duration of postoperative analgesia following  laparoscopic cholecystectomy using Inj Bupivacaine 0.25 percent.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 75.00 Year(s)(—)
性别
All

入选标准

  • Patients posted for elective laparoscopic cholecystectomy under general anaesthesia
  • Patients aged between 18 to 75y
  • Patients belonging to American Society of Anaesthesiologists Physical status 1 and 2.

排除标准

  • Known allergy to the local anaesthetics given.
  • Patients with chronic pain on slow-release preparations of opioid, drug or alcohol abuse.
  • Patients with dementia or cognitive problems.
  • Patients with BMI greater than 35kg/m
  • Known case of Diabetes mellitus.

结局指标

主要结局

To assess the duration of postoperative analgesia following laparoscopic cholecystectomy

时间窗: For first 24 postoperative hours

次要结局

  • To evaluate analgesic consumption in first 24 postoperative hours.(To assess the incidence of adverse effects like nausea, vomiting.)

研究者

发起方
Dr Rekha S
申办方类型
Other []
责任方
Principal Investigator
主要研究者

Dr Rekha S

Dr B R Ambedkar medical college and hospital

研究点 (1)

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