Factors Affecting Abdominal Compliance During CO2 Insufflation in Laparoscopic Abdominal Surgery

Completed

• Conditions: Laparoscopic Surgery

• Registration Number: NCT06396351
• Lead Sponsor: Ankara University

Brief Summary

The authors aimed to evaluate factors influencing abdominal compliance in laparoscopic abdominal surgery.

Detailed Description

During laparoscopic surgery, pneumoperitoneum is achieved by insufflating carbon dioxide (CO2) gas into the abdominal cavity to create a safe working space. Pneumoperitoneum-induced elevation in intra-abdominal pressure (IAP) can result in various complications. Abdominal compliance (AC), represents the slope of the P-V curve of the abdominal cavity and is a measure of the ease of abdominal dilatation, is important to balance between surgical safety and complications. The aim of this study was to determine the effect of demographic and anatomic variables on AC.

The study included 90 patients who underwent laparoscopic abdominal surgery. Subcutaneous adipose tissue and abdominal muscle thickness were measured ultrasonographically. Mean AC was calculated during insufflation using the formula (ΔV/ΔP). The relationship between demographic and anatomic variables and AC was investigated

Study Timeline

• Study Start: 2022-08-01
• Primary Completion: 2022-11-30
• Study Completion: 2022-11-30
• Status Verified: 2024-04
• Study First Submitted: 2024-04-25
• Study First Submitted QC: 2024-04-29
• Last Update Submitted: 2024-04-29
• Study First Posted: 2024-05-02
• Last Update Posted: 2024-05-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Aged between 18 and 82 years ASA class I-III Elective abdominal surgery with laparoscopic technique

Exclusion Criteria

Aged below 18 and above 82 ASA IV-V

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The factors affecting abdominal compliance	From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery	Effect of rectus muscle thickness and lateral abdominal muscle group thickness on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

Secondary Outcome Measures

Name	Time	Method
The factors affecting abdominal compliance	From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery	Effect of subcutaneous adipose tissue thickness on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation.

Trial Locations

Locations (1)

Ankara University Medical School Anesthesiology and ICU Department; 🇹🇷 Ankara, Turkey