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Intradialytic Aerobic Exercise in CKD Patient

Not Applicable
Completed
Conditions
Chronic Kidney Diseases
Registration Number
NCT06137937
Lead Sponsor
Universitas Padjadjaran
Brief Summary

Intradialytic aerobic exercise is not effective in increasing hemodialysis adequacy but is effective in improving physical performance in twice-weekly hemodialysis patients.

Detailed Description

Uremic myopathy occurs in 60-75% of Chronic Kidney Disease (CKD) patients undergoing hemodialysis, which causes a decrease in muscle strength and physical performance. Increasing dialysis adequacy is beneficial in reducing the impact of uremia on muscles. Intradialytic aerobic exercise in thrice-weekly hemodialysis patients has improved dialysis adequacy and physical performance. This study aims to determine the effect of intradialytic aerobic exercise on improving dialysis adequacy and physical performance in twice-weekly hemodialysis patients.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
34
Inclusion Criteria
  • End Stage Renal Disease Patient stage 5 with Glomerular Filtration Rate <15mL/minute/1.73m2 aged 25-54 years undergoing hemodialysis two times per week for three months to five years
  • Hemoglobin levels > 8mg/dl
  • Mini-Mental State Examination (MMSE) score of ≥24
  • Hamilton Depression Rating Scale (HDRS) score <25
Exclusion Criteria
  • Received aerobic exercise in the last 3 months
  • History of hospitalization in the last 3 months
  • Access for hemodialysis circulation via the femoral vein.
  • IMT <18,5 (underweight) dan ≥35 (obese class II)
  • Non-stable cardiovascular disease, uncontrolled glucose, acute infection disease

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Kt/Veight weeks

Dialysis adequacy (Kt/V) and physical performance test with a Short Physical Performance Battery (SPPB) were evaluated before and after the intervention

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Al Ihsan Hospital

🇮🇩

Bandung, West Java, Indonesia

Al Ihsan Hospital
🇮🇩Bandung, West Java, Indonesia

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