Intradialytic Aerobic Exercise in CKD Patient
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- Kt/V
研究概览
简要总结
Intradialytic aerobic exercise is not effective in increasing hemodialysis adequacy but is effective in improving physical performance in twice-weekly hemodialysis patients.
详细描述
Uremic myopathy occurs in 60-75% of Chronic Kidney Disease (CKD) patients undergoing hemodialysis, which causes a decrease in muscle strength and physical performance. Increasing dialysis adequacy is beneficial in reducing the impact of uremia on muscles. Intradialytic aerobic exercise in thrice-weekly hemodialysis patients has improved dialysis adequacy and physical performance. This study aims to determine the effect of intradialytic aerobic exercise on improving dialysis adequacy and physical performance in twice-weekly hemodialysis patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
盲法说明
The sample in this study was determined randomly using a computer; subjects in the treatment group underwent routine hemodialysis by committing to an intradialysis aerobic exercise program
入排标准
- 年龄范围
- 25 Years 至 54 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •End Stage Renal Disease Patient stage 5 with Glomerular Filtration Rate <15mL/minute/1.73m2 aged 25-54 years undergoing hemodialysis two times per week for three months to five years
- •Hemoglobin levels > 8mg/dl
- •Mini-Mental State Examination (MMSE) score of ≥24
- •Hamilton Depression Rating Scale (HDRS) score <25
排除标准
- •Received aerobic exercise in the last 3 months
- •History of hospitalization in the last 3 months
- •Access for hemodialysis circulation via the femoral vein.
- •IMT <18,5 (underweight) dan ≥35 (obese class II)
- •Non-stable cardiovascular disease, uncontrolled glucose, acute infection disease
结局指标
主要结局
Kt/V
时间窗: eight weeks
Dialysis adequacy (Kt/V) and physical performance test with a Short Physical Performance Battery (SPPB) were evaluated before and after the intervention
次要结局
未报告次要终点
研究者
Irma Ruslina Defi
Principal Investigator
Universitas Padjadjaran