The Role of Intravitreal Glucose in Macular Thinning Following Surgery for Retinal Detachment or Epimacular Membrane

Completed

• Conditions: Macular Thinning; Vitrectomy

• Registration Number: NCT02210481
• Lead Sponsor: CHU de Reims

Brief Summary

Comparison between intravitreous glucose rate and macular thinning measured by Ocular Coherence Tomography (OCT) at 3 months post vitrectomy for retinal detachment or epimacular membrane. Hypothesis : Association between post-operative macular thickness and intravitreous glucose rate

Detailed Description

Comparison between intravitreous glucose rate and macular thinning measured by OCT at 3 months post vitrectomy for retinal detachment or epimacular membrane. The cohort is divided in 2 groups, one with the thinnest macular measurement under 190µm, and the others above 190µm. We are looking for a correlation between increasing glucose rates and decreased macular thickness.

Study Timeline

• Study Start: 2014-02
• Study First Submitted: 2014-08-05
• Study First Submitted QC: 2014-08-05
• Study First Posted: 2014-08-06
• Primary Completion: 2014-11
• Study Completion: 2014-12
• Status Verified: 2017-11
• Last Update Submitted: 2017-11-09
• Last Update Posted: 2017-11-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• patient who underwent vitrectomy for retinal detachment or epimacular membrane

Exclusion Criteria

• patient suffering of diabetes,
• recurrence of retinal detachment,
• age-related macular degeneration,
• post surgical macular oedema

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
macular thickness measured by OCT	3 months post-operatively

Secondary Outcome Measures

Name	Time	Method
visual acuity	3 months post-operatively

Trial Locations

Locations (1)

Centre Hospitalier Universitaire de Reims; 🇫🇷 Reims, France