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A clinical trial to study the effects of two drugs, D-9998 and CG-315 in patients with acute pain after orthopedic operation or injuries.

Phase 2
Completed
Registration Number
CTRI/2009/091/001056
Lead Sponsor
Sun Pharmaceutical Industries Ltd.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
200
Inclusion Criteria

1.Male or female patients aged between 18 - 65 years.
2.Patient suffering from pain after orthopedic operation or due to injury.
3.Patient or his/her care taker willing to give their informed consent.

Exclusion Criteria

1.Pregnant, lactating women or women of childbearing age who are not using an acceptable method of birth control.
2.Patients having hypersensitivity to the drug or other opioid analgesics.
3.Patients having risk of a hepatic encephalopathy.
4.Patient with cholestasis.
5.Patients with epilepsy, with a history of seizure, or patients with a recognized risk for seizure.
6.Patient with myasthenia gravis.
7.Patient addicted to alcohol.
8.Patient with liver disease.
9.Patients receiving SSRIs, TCAs or other tricyclic compounds, MAOIs, or neuroleptics.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in the severity of pain on the VAS.Timepoint: Day 0, Day 7
Secondary Outcome Measures
NameTimeMethod
Clinical global impression on improvementTimepoint: Day 7
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