Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19

Phase 3

Completed

• Conditions: COVID
• Interventions: Drug: Chloroquine or hydroxychloroquine; Drug: zinc

• Registration Number: NCT04447534
• Lead Sponsor: Tanta University

Brief Summary

we want to investigate if zinc supplementation enhance the clinical efficacy of chloroquine in treatment of COVID-19.

Detailed Description

we want to investigate if zinc supplementation enhance the clinical efficacy of chloroquine in treatment of COVID-19. As, zinc may be of value in these cases and may be of value in enhancing chloroquine effect.

Study Timeline

• Study Start: 2020-06-23
• Study First Submitted: 2020-06-23
• Study First Submitted QC: 2020-06-23
• Study First Posted: 2020-06-25
• Primary Completion: 2020-07-15
• Study Completion: 2020-08-15
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-23
• Last Update Posted: 2022-04-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 191

Inclusion Criteria

• Patients with positive COVID-19.

Exclusion Criteria

• Contraindications or hypersensitivity to chloroquine.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Chloroquine or hydroxychloroquine with zinc	Chloroquine or hydroxychloroquine	Chloroquine or hydroxychloroquine with zinc
Chloroquine or hydroxychloroquine with zinc	zinc	Chloroquine or hydroxychloroquine with zinc
Chloroquine or hydroxychloroquine	Chloroquine or hydroxychloroquine	Chloroquine or hydroxychloroquine alone

Primary Outcome Measures

Name	Time	Method
Number of patients with improvement or mortality	2 weeks	The number of patients with improvement or mortality.

Trial Locations

Locations (1)

Tanta university hospital, Assuit University, Ainshams University; 🇪🇬 Tanta, Egypt