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临床试验/NCT01920646
NCT01920646已完成不适用

The Effect of African Leafy Vegetables on Nutritional Status (Including Iron, Zinc and Vitamin A Status) of School Children Residing in Semi-rural Farm Community in the North West Province of South Africa

North-West University, South Africa1 个研究点 分布在 1 个国家目标入组 171 人开始时间: 2012年2月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
171
试验地点
1
主要终点
Change in nutritional status of school children (nutritional status measured by: blood haemoglobin, serum ferritin, serum zinc and serum retinol)

研究概览

简要总结

The combination of poverty-related infectious and lifestyle-related non-communicable diseases, both driven by malnutrition, causes a high burden for South Africa. Healthy and nutritious diets for populations depend on availability and accessibility of a variety of plant and animal foods, within a context that promotes and supports healthy behaviour. Food based strategies, such as supplementation, food fortification, and diversification of crops, are used to achieve optimal dietary requirements to combat malnutrition, including micronutrient deficiencies. A more sustainable food based strategy is the (promotion of) use of indigenous and traditional foods, such as African Leafy Vegetables (ALVs). Unfortunately, several studies from all over Africa have shown that there is a shift from traditional diets as result of the preparing techniques and the absence of women in homes. Furthermore, indigenous and traditional foods are considered as "poor people's food".

Against this background, a joint project between South Africa, Kenya and Benin is designed to fill the gaps in knowledge in these countries regarding the availability, acceptability and consumption and evidenced based benefits of foods from local biodiversity. The main aim of the study in South Africa is to provide empirical evidence of how the role of biodiversity can be translated into improved health status in contemporary poor rural and urban communities in the North West Province of South Africa. In order to achieve this it is important to gain knowledge on the possibility of using ALVs as a strategy to alleviate micronutrient deficiencies. Therefore an intervention study to determine the effect of selected ALV on the nutritional status (including zinc, iron, and vitamin A status) of school children (grade R-4) residing in contemporary poor rural community in the North West Province, South Africa has been designed.

研究设计

研究类型
Interventional
分配方式
Randomized

入排标准

年龄范围
6 Years 至 12 Years(Child)
性别
All
接受健康志愿者
是

入选标准

  • •apparently healthy and had no signs and symptoms of acute illness at the time of baseline blood collection
  • •attending grade R - 4 of one of the selected schools

排除标准

  • •Children with a haemoglobin concentration <8 g/dL were excluded from the study and referred for medical treatment.
  • •Children who received micronutrient supplements were also excluded from the study.

研究组 & 干预措施

Control

No Intervention

normal school meal as daily meal (5 days/weeks) for 3 months

ALV

Experimental

300 gram cooked African leafy vegetables and school meal starch as daily school meal (5 days/weeks) for 3 months.

Selected African leafy vegetables:Amaranthus cruentus (amaranth), Vigna unguiculata (cowpea), Cleome gynandra (spiderplant), and Cucurbita maxima (pumpkin).

干预措施: ALV (Other)

结局指标

主要结局

Change in nutritional status of school children (nutritional status measured by: blood haemoglobin, serum ferritin, serum zinc and serum retinol)

时间窗: three months

次要结局

  • Change in nutritional status of school children (nutritional status measured by: height-for-age z-score, weight-for-age z-score and BMI-for-age z-score)(three months)

研究者

发起方
North-West University, South Africa
申办方类型
Other
责任方
Principal Investigator
主要研究者

Marinka van der Hoeven

Mrs Marinka van der Hoeven

North-West University, South Africa

研究点 (1)

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