Effectiveness of Gum Chewing on Ileus in Chinese Colorectal Patients Underwent Laparoscopic Colorectal Surgery

Not Applicable

Completed

• Conditions: Colorectal Cancer
• Interventions: Other: bubble gum

• Registration Number: NCT02419586
• Lead Sponsor: Shum Nga Fan

Brief Summary

Gum chewing group will have less ileus and early resume of bowel motion than control group.

Detailed Description

The standardize surgical techniques, less used of epidural analgesia, early ambulation and used of naso-gastric tube for decompression are aimed to reduce the paralytic ileus after abdominal surgery . Most Western studies have examined and found that gum chewing are able to prevent postoperative ileus or promotes early bowel function after abdominal surgery.

Study Timeline

• Study Start: 2015-01
• Study First Submitted: 2015-03-04
• Study First Submitted QC: 2015-04-14
• Study First Posted: 2015-04-17
• Primary Completion: 2015-12
• Study Completion: 2016-06
• Status Verified: 2018-06
• Last Update Submitted: 2018-06-19
• Last Update Posted: 2018-06-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

• Patients with newly diagnosed colorectal cancer undergoing laparoscopic resection in in Queen Mary Hospital
• At least 18 years
• Speak Cantonese
• Able to follow study protocol and chewing gum study

Exclusion Criteria

• Cognitive disability
• Requirement of epidural analgesia
• Requirement of intensive care unit/ High dependency unit care postoperatively
• Inability to chew
• Presence of procedure other than colorectal resection
• Non Chinese

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
bubble gum chewing and routine care	bubble gum	Start chewing gum on postoperative day at three times daily with no more than 30 minutes till discharged

Primary Outcome Measures

Name	Time	Method
Time to first flatus	from postoperative day 0 till an expected average of day 7	Time to passage of flatus after surgery was significantly shorter in the intervention group (22 vs 39 hours, p=0.007).

Secondary Outcome Measures

Name	Time	Method
Time to first bowel movement,	from postoperative day 0 till an expected average of day 7	The first bowel motion also occurred earlier in the intervention group (22 vs 52 hours, p\<0.001)
Time to first sense of hunger	from postoperative day 0 till an expected average of day 7	Patients in the intervention group also noticed feeling of hunger earlier (17 vs 40 hours, p\<0.001).
Length of stay	from postoperative day 0 till an expected average of day 7	There is no difference in length of stay between intervention group or control group

Trial Locations

Locations (1)

Queen Mary Hospital; 🇨🇳 Hong Kong, China