Color-dependent Melatonin Suppression

Not Applicable

Completed

• Conditions: Melatonin
• Interventions: Device: Light - standard; Device: Light - alternate

• Registration Number: NCT02936674
• Lead Sponsor: VA Palo Alto Health Care System

Brief Summary

The purpose of this study is to examine the effects of complex, broad-band spectra light on the production of melatonin in humans.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-10
• Study First Submitted: 2016-10-07
• Study First Submitted QC: 2016-10-17
• Study First Posted: 2016-10-18
• Primary Completion: 2017-06
• Study Completion: 2017-06
• Status Verified: 2018-01
• Last Update Submitted: 2018-01-03
• Last Update Posted: 2018-01-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Stable health
• Normal color vision
• Normal hearing
• 18-35 years old

Exclusion Criteria

• Significant depressive symptoms
• Pregnant or nursing
• Ocular pathologies
• Unstable or severe medical or psychiatric condition
• Extreme morning/evening type
• Regular smoker
• Use of medications that impact ocular function
• Alcohol use disorder
• Use of illegal drugs
• Irregular use of antihistamines, antidepressants, or sleeping medications

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Light 2	Light - standard	Light 2 will be a standard LED bulb.
Light 1	Light - alternate	Light 1 will have an altered color composition as compared with a standard LED bulb.

Primary Outcome Measures

Name	Time	Method
Melatonin suppression	4 Hours	The amount of declination of salivary melatonin concentrations between the start of the light and the end of the light (4 hours later) will be compared between the conditions.

Trial Locations

Locations (1)

VA Palo Alto Health Care System; 🇺🇸 Palo Alto, California, United States