NCT01748409已完成不适用
Physiopathological Study of Autonomic Failure in Parkinson's Disease : a Monocentric Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 47
- 试验地点
- 2
- 主要终点
- Evaluate association between clinical autonomic failure and neuropathological autonomic failure on biopsies.
研究概览
简要总结
The aim of the study is to evaluate the autonomic failure in Parkinson's disease by clinical, electrophysiological and neuropathological examination.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with Parkinson's disease
- •ages 45 to 80 years, both genders
- •patients who signed informed consent
排除标准
- •autonomic function modifying treatment
- •pre-existing neuropathy or risk factors for neuropathy
- •colonic disorders
- •coagulation disorders (may be due to treatment)
结局指标
主要结局
Evaluate association between clinical autonomic failure and neuropathological autonomic failure on biopsies.
时间窗: 3 months
the main objective is to look after associations between : * anatomopathological signs of autonomic nervous system disorders seen on biopsies AND * clinical signs of signs of autonomic nervous system disorders seen through functional tests or through symptoms indicated by the patient on questionaries.
次要结局
- Evaluate association between autonomic failure and severity factors in Parkinson's disease(3 months)
- Evaluate consequences of autonomic failure on quality of life and sleep quality(3 months)
研究者
研究点 (2)
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