Alterations in Urine pH With Differing Diet Net Acid Loads
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- high acid diet
研究概览
简要总结
Presently, the gold standard for testing diet acid intake is a urine collection done for many hours, usually 24 hours, which must be analyzed in a research lab for "net acid excretion". So, getting information about diet acid intake is difficult. Many people have suggested doing a much simpler test, which is checking the pH of the urine when you wake up. But, no one has studied if this simpler method is a valid method for estimating the 24 hour net acid excretion. Diet acid load may be important in many diseases associated with aging, such as loss of bone and muscle, and the development of kidney disease.
详细描述
the primary outcome variable is morning urine pH and 24 hour urine net acid excretion
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •no medical or psychological problems
- •able to come to UCSF for study
排除标准
- •pregnant or trying to become pregnant
- •abnormal screening labs
- •anyone unable to follow study directions
结局指标
主要结局
high acid diet
时间窗: 6 months
correlation between first morning urine pH and 24 hour net acid excretion
low acid diet
时间窗: 6 months
correlation between first morning urine pH and 24 hour net acid excretion
次要结局
未报告次要终点
