Urine pH and Diet Net Acid Load
- Conditions
- Healthy
- Interventions
- Other: high or low acid diet
- Registration Number
- NCT02116595
- Lead Sponsor
- University of California, San Francisco
- Brief Summary
Presently, the gold standard for testing diet acid intake is a urine collection done for many hours, usually 24 hours, which must be analyzed in a research lab for "net acid excretion". So, getting information about diet acid intake is difficult. Many people have suggested doing a much simpler test, which is checking the pH of the urine when you wake up. But, no one has studied if this simpler method is a valid method for estimating the 24 hour net acid excretion. Diet acid load may be important in many diseases associated with aging, such as loss of bone and muscle, and the development of kidney disease.
- Detailed Description
the primary outcome variable is morning urine pH and 24 hour urine net acid excretion
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
- no medical or psychological problems
- able to come to UCSF for study
- pregnant or trying to become pregnant
- Hg < 10
- abnormal screening labs
- anyone unable to follow study directions
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description low acid diet high or low acid diet - feeding a high acid diet x 24 hrs high or low acid diet 2 diets, one low and one high net acid loads
- Primary Outcome Measures
Name Time Method high acid diet 6 months correlation between first morning urine pH and 24 hour net acid excretion
low acid diet 6 months correlation between first morning urine pH and 24 hour net acid excretion
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UCSF
🇺🇸San Francisco, California, United States