Comparison of measured versus predicted blood propofol concentrations in children undergoing spinal surgery
- Conditions
- Children undergoing spinal surgery have propofol anaesthesia delivered by a computerised syringe driver (Target Controlled Infusion or TCI). Spinal surgery is associated with major blood loss. This can result in either over or under-delivery ofpropofol, both can result in serious problems during anaesthesia. .Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
- Registration Number
- EUCTR2012-003790-25-GB
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Patients included (All of the below):
1. Children between the age of 5 and 18 years
2. Undergoing spinal surgery lasting more than 3 hours
3. Receiving Propofol intravenous anaesthesia as the primary anaesthetic.
Are the trial subjects under 18? yes
Number of subjects for this age range: 20
F.1.2 Adults (18-64 years) no
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Patients excluded (Either of the below)
1. Surgery expecting to last less than 3 hours
2. Patients with major hepatic or renal disease
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method