Effect of midazolam-fentanyl versus propofol-ketamine sedation for peribulbar nerve block

Not Applicable

• Conditions: Sedation in peribulbar block cataract surgery.; Senile cataract, unspecified

• Registration Number: IRCT2013072911676N2
• Lead Sponsor: Vice chancellor for Research, Tehran University of Medical Sciences and Health Services

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Inclusion creteria: ASA 1-3; patients older than 60 yr of age (max 80 yr) undergoing cataract extraction and intraocular lens implantation on an ambulatory surgery.
Patients were excluded if: they weighed 150% of their ideal body weight; had ischemic heart disease; had uncontrolled hypertension (systolic/diastolic blood pressure 180/ 110 mm Hg) or had a history of allergy to ketamine, propofol, or local anesthetic drugs; had a history of psychiatric disorders; suffered memory or cognitive dysfunction; had ingested a opoids, tranquilizer or psychoactive drug within 2 wk of surgery.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patient satisfaction. Timepoint: 3 to 5 min after injection. Method of measurement: Question.;Quality of sedation. Timepoint: During injection. Method of measurement: Scale.

Secondary Outcome Measures

Name	Time	Method
Hemodynamic (systolic, diastolic and mean BP, heart rate). Timepoint: 1 min after sedation and 3 min after injection. Method of measurement: Automated hemodynamic monitoring , electrocardiogram.;Spo2. Timepoint: 1-min after sedation and at 3 min after injection PBB. Method of measurement: Pulse oximeter.;Degree of respiratory depression. Timepoint: 1-min after sedation and at 3 min after injection PBB. Method of measurement: Table of score.;Air way intervention. Timepoint: 1-min after sedation and at 3 min after injection PBB. Method of measurement: Table of score.;Side effects of drugs. Timepoint: During operation. Method of measurement: Record.