A Study to assess the effects of Different Positive End Expiratory Pressure (PEEP) Levels for evaluation of improvement in PaO2(gas exchange) by doing serial ABG in patients undergoing One Lung Ventilation in thoracic surgeries under general anesthesia.

Not yet recruiting

• Conditions: Diseases of the respiratory system,

• Registration Number: CTRI/2023/11/059998
• Lead Sponsor: Sawai Maan Singh Medical college and hospital

Brief Summary

Our aim is to evaluate the effect of various PEEP(positive end expiratory pressure) levels on PaO2 (gas exchange) in one lung ventilation in patients undergoing thoracic surgery under general anesthesia.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-11-19
• Study Start: 2023-12-20

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• ) Pt. willing to give written and Informed consent.
• 2. Age >18yrs 3) Patient undergoing Elective thoracic Surgery.
• 4. ASA Grade- II and III 5) OLV lasting ≥ 60mins.

Exclusion Criteria

• lung reduction surgery Pneumonectomy patients with severe COPD with preoperative forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC) ratio, expressed as a percentage (FEV1/FVC%) < 60% presence of large bullae, pleural diseases and/or acute or chronic.
• uncompensated cardiac disease.
• ASA Grade –IV.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To see the effect of various PEEP levels on PaO2/FiO2 ratio by ABG analysis	45minutes

Secondary Outcome Measures

Name	Time	Method
1. Hemodynamic variation like Heart Rate, Systolic BP, Diastolic BP.	2.Various complications

Trial Locations

Locations (1)

SMS Medical College And Hospital; 🇮🇳 Jaipur, RAJASTHAN, India

SMS Medical College And Hospital

🇮🇳Jaipur, RAJASTHAN, India

Dr Indu Verma

Principal investigator

9413622967

dr.induverma@gmail.com