Diagnostic Usefulness of Different Types of Gastrointestinal Endoscopic Investigations.
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 5,000
- 试验地点
- 1
- 主要终点
- All confirmed colorectal cancer cases that were diagnosed via colonoscopy.
研究概览
简要总结
The number of endoscopies performed varies greatly between different countries and does not reflect variations in disease incidents. The costs of unnecessary endoscopies are significant and with a better selection of which patients need to be examined with endoscopy, resources could be saved in healthcare, and a better triage would mean that malignancies and other more serious conditions do not have to wait. An example of unnecessary endoscopy is a colonoscopy in patients with irritable bowel syndrome or gastroscopy in patients with functional dyspepsia.
The purpose of the project is, among other things:
- What diagnostic benefit have gastroscopy, colonoscopy, capsule endoscopy and double balloon enteroscopy for different indications in different age groups?
- What are the risks of this type of examination?
- Can patients be better selected based on symptoms, psychometric data or laboratory findings to reduce the number of unnecessary examinations and prioritize those that should be scooped up first?
- Can changed calling methods reduce the number of late cancellations and rebookings and missed patients?
详细描述
1: Identification of colorectal cancer in Örebro Region - Effectiveness of Standardised Course of Care.
Introduction: To shorten time to diagnosis of suspected colorectal cancer (CRC) in Sweden, CRC was included in the "standardised course of care" (SCC) in 2016. However, not all patients with CRC are referred via the SCC, and CRC is also found in patients undergoing a routine colonoscopy.
Objective: To identify CRC cases in the Örebro Region and how they were identified. Furthermore, to investigate the reasons for and possible effect of not being included in the SCC-CRC for cases found via colonoscopy.
Methods: Reviewing medical records of patients with CRC referred to the Clinic of Surgery in the Örebro Region in 2016-2018 (n=459).
The information recalled from the journals includes diagnostic pathway of CRC discovery, age, gender, Body Mass Index (BMI), Hb-value, date of referral to colonoscopy, date of preformed colonoscopy, referral route (SCC-CRC or non-CRC-SCC), reasons for referral (including SCC-CRC criteria) and patient symptoms. Furthermore, we will gather data of tumor localization (caecum; ascending colon; splenic flexure; transverse colon; hepatic flexure; descending colon; sigmoid and rectum), TNM-stage of the tumor, [11] tumor differentiation (high grade or low grade tumor), and source of referral (referral by general practitioner or referral by hospital physician).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients who underwent a diagnostic diagnostic procedure at the endoscopy unit at the University Hospital Örebro.
排除标准
- •Patients <18 years
结局指标
主要结局
All confirmed colorectal cancer cases that were diagnosed via colonoscopy.
时间窗: between September 2016 and December 2018
The proportion of patients that was admitted to the department of surgery with confirmed colorectal cancer, diagnosed according to the standardized course of care for colorectal cancer.
Proportion of patients that was diagnosed with colorectal cancer. with colorectal cancer
时间窗: between September 2016 and December 2018
All patients that were admitted to the endoscopy unit according to the standardized course of care for colorectal cancer.
Presence of upper GI pathology
时间窗: between Jan 2019-April 2020
The proportion of upper GI pathology in all patients \<50 years who were admitted for a gastroscopy
次要结局
- symptom characteristics of colorectal cancer 4(January 2016 and December 2018)
- patient characteristics of colorectal cancer 4(January 2016 and December 2018)
- patient characteristics of colorectal cancer 6(January 2016 and December 2018)
- symptom characteristics of colorectal cancer 6(January 2016 and December 2018)
- route of colorectal cancer diagnosis 1(January 2016 and December 2018)
- route of colorectal cancer diagnosis 2(January 2016 and December 2018)
- Localization of colorectal cancer(January 2016 and December 2018)
- tumor characteristics of colorectal cancer 1(January 2016 and December 2018)
- tumor characteristics of colorectal cancer 2(January 2016 and December 2018)
- symptom characteristics of colorectal cancer 1(January 2016 and December 2018)
- symptom characteristics of colorectal cancer 2(January 2016 and December 2018)
- symptom characteristics of colorectal cancer 3(January 2016 and December 2018)
- symptom characteristics of colorectal cancer 5(January 2016 and December 2018)
- symptom characteristics of colorectal cancer 7(January 2016 and December 2018)
- patient characteristics of colorectal cancer 1(January 2016 and December 2018)
- patient characteristics of colorectal cancer 2(January 2016 and December 2018)
- patient characteristics of colorectal cancer 3(January 2016 and December 2018)
- patient characteristics of colorectal cancer 5(January 2016 and December 2018)
- patient characteristics of colorectal cancer 7(January 2016 - December 2018)
研究者
Michiel van Nieuwenhoven
Md, MSc, associate professor
Region Örebro County