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Safety, Tolerability, and Immunogenicity of Zoster Vaccine Live (ZOSTAVAXâ?¢) in Healthy Adults in India (V211-025)

Phase 3
Completed
Registration Number
CTRI/2012/08/002922
Lead Sponsor
Merck Sharp and Dohme
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
250
Inclusion Criteria

A subject will be eligible to participate in this study if all of the following criteria apply:

a.Greater than or equal to 50 years of age.

b.Females have a negative pregnancy test and use an acceptable method of birth control, or are postmenopausal

c.Any underlying chronic illness must be in stable condition.

Note: We have entered maximum age of 99 yrs, as there is no upper limit defined in the study protocol, the same is approved by the directorate(DCGI).

Exclusion Criteria

A subject will not be eligible to participate in this study if any of the following criteria apply:

a.History of hypersensitivity reaction to any vaccine component

b.Prior history of HZ

c.Previously received a varicella or zoster vaccine

d.Pregnant or breastfeeding

e.Have recently received blood products other than autologous blood transfusion

f.Use of immunosuppressive therapy

g.Known or suspected immune dysfunction

h.Use of nontopical antiviral therapy with activity against herpes virus

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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