Do Women's Quality of Life, Sexual Life and Psychological State Differ Between Patients Undergoing Fresh and Frozen Embryo Transfers: a Prospective Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 232
- 试验地点
- 1
- 主要终点
- Clinical pregnancy rate
研究概览
简要总结
Women's quality of life, sexual life and psychological state would affect the success of embryo transfer. The primary purpose of the study is to compare women's quality of life, sexual life and psychological state using validated forms between those undergoing fresh embryo transfer and those undergoing frozen embryo transfer.
详细描述
There are two types of embryo transfers; fresh and frozen embryo transfers. Studies have been conducted to compare success rates between fresh and frozen embryo transfers. However, most studies have not taken into consideration women's quality of life, sexual life and psychological state in comparing fresh embryo transfer with frozen embryo transfers. These all parameters are confounding factors that may influence the success of embryo transfer. The purpose of this study is to compare women's quality of life, sexual life and psychological state using validated forms between those undergoing fresh embryo transfer and those undergoing frozen embryo transfer. The following forms will be used: expanded version of the inventory of depression and anxiety symptoms (IDAS-II), Beck Anxiety inventory (BAI), Short Form Survey (SF-36) and Female Sexual Function Index (FSFI. This study can provide evidence regarding the association between women's quality of life, sexual life and psychological state and embryo transfer success.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 39 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Age between 20 - 39 years
- •Body mass index between 18 -3 5 kg/m2
- •Anti-mullerian hormone levele >1.1 ng/ml or antral follicle count > 8
- •fresh or frozen embryo transfer using middle-quality or good-quality day 3 or 5 embryos
排除标准
- •Age below 20 or over 39 years
- •Uterine malformations
- •Hypo or hyperthyroidism
- •Diabetes mellitus
- •Previous history of psychiatric disorders
- •Use of psychiatric medications
- •Systemic disorders (hypertension, chronic liver/kidney/heart problems)
结局指标
主要结局
Clinical pregnancy rate
时间窗: At around 7 weeks of gestation
Clinical pregnancy is defined as the presence of intrauterine fetal heartbeat at around 7 weeks of gestation.
次要结局
- Implantation rate(At around 6 weeks of gestation)
- Live birth rate(24 completed weeks of gestation)
研究者
Mehmet Resit Asoglu
Associate professor
Bahceci Health Group