Do Women's Quality of Life, Sexual Life and Psychological State Differ Between Patients Undergoing Fresh and Frozen Embryo Transfers: a Prospective Study
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 232
- Locations
- 1
- Primary Endpoint
- Clinical pregnancy rate
Study Overview
Brief Summary
Women's quality of life, sexual life and psychological state would affect the success of embryo transfer. The primary purpose of the study is to compare women's quality of life, sexual life and psychological state using validated forms between those undergoing fresh embryo transfer and those undergoing frozen embryo transfer.
Detailed Description
There are two types of embryo transfers; fresh and frozen embryo transfers. Studies have been conducted to compare success rates between fresh and frozen embryo transfers. However, most studies have not taken into consideration women's quality of life, sexual life and psychological state in comparing fresh embryo transfer with frozen embryo transfers. These all parameters are confounding factors that may influence the success of embryo transfer. The purpose of this study is to compare women's quality of life, sexual life and psychological state using validated forms between those undergoing fresh embryo transfer and those undergoing frozen embryo transfer. The following forms will be used: expanded version of the inventory of depression and anxiety symptoms (IDAS-II), Beck Anxiety inventory (BAI), Short Form Survey (SF-36) and Female Sexual Function Index (FSFI. This study can provide evidence regarding the association between women's quality of life, sexual life and psychological state and embryo transfer success.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 20 Years to 39 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Age between 20 - 39 years
- •Body mass index between 18 -3 5 kg/m2
- •Anti-mullerian hormone levele >1.1 ng/ml or antral follicle count > 8
- •fresh or frozen embryo transfer using middle-quality or good-quality day 3 or 5 embryos
Exclusion Criteria
- •Age below 20 or over 39 years
- •Uterine malformations
- •Hypo or hyperthyroidism
- •Diabetes mellitus
- •Previous history of psychiatric disorders
- •Use of psychiatric medications
- •Systemic disorders (hypertension, chronic liver/kidney/heart problems)
Outcomes
Primary Outcomes
Clinical pregnancy rate
Time Frame: At around 7 weeks of gestation
Clinical pregnancy is defined as the presence of intrauterine fetal heartbeat at around 7 weeks of gestation.
Secondary Outcomes
- Implantation rate(At around 6 weeks of gestation)
- Live birth rate(24 completed weeks of gestation)
Investigators
Mehmet Resit Asoglu
Associate professor
Bahceci Health Group