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Insomnia Magnetic Resonance Spectroscopy (MRS) imaging sleep study

Not Applicable
Completed
Conditions
Insomnia Disorder
Mental Health - Other mental health disorders
Registration Number
ACTRN12612000050853
Lead Sponsor
niversity of Sydney
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
47
Inclusion Criteria

1. Symptoms of Insomnia Disorder as diagnosed by the Diagnostic and
Statistical Manual of Mental Disorders, Fifth Edition criteria for insomnia
disorder (APA, 2013) specifically: Difficulty initiating or maintaining sleep or
waking up too early for at least 3 nights per week, for at least 3 months,
with adequate opportunity and circumstances for sleep
2. Stable sleep/wake schedule with no shift work
3. Able to give informed, written consent
4. Fluent speaker of English
5. Referred by a sleep physician to have a routine sleep study as part of Medicare

Exclusion Criteria

1. Pregnancy or lactation
2. Active illicit substance use or alcohol/caffeine dependence
3. Medications that interfere with sleep (within 1 month of assessment)
4. Psychiatric disorders, other than mild to moderate depression (on the
Depression Anxiety Stress Scales)
5. Another sleep disorder evaluated by a Sleep Physician / Sleep
Psychologist that better explains the complaint of sleep loss.
6. Severe cognitive impairment that does not allow patients to consent or
follow study instructions
7. Overnight shift workers and recent time-zone travel (within last 2
months)
8. Actively treated sleep disorder (e.g. CPAP/CBT-I)

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To use MRS in order to compare and contrast brain neurochemistry within specific and highly defined insomnia sub types (insomnia sufferers with and without hyperarousal).[A comparison will be made between controls and insomnia sufferers with hyperarousal. This will take place at one time point only.]
Secondary Outcome Measures
NameTimeMethod
il[Nil]
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