Stroke Survival in Municipalities: Impact of Geographic Proximity to First- and Second-degree Relatives

• Conditions: Stroke

• Registration Number: NCT04072120
• Lead Sponsor: University of Oslo

Brief Summary

Our key objective will be to investigate if geographic proximity to first- and second-degree relatives has an influence on post-acute stroke survival and use of health and social services. We will also model and map spatial variation in stroke and cardiovascular disease (CVD) incidence and mortality and see if some of the variation is due to spatial clustering of familial risk. The study will use innovative approaches to large-scale registry and survey data and statistical analysis on the full Norwegian population. We will integrate multigenerational and geographical information. This will enable us to assess key determinants on stroke survival and use of health and social care at municipality level.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-15
• Study First Submitted: 2019-08-22
• Study First Submitted QC: 2019-08-27
• Study First Posted: 2019-08-28
• Status Verified: 2020-05
• Last Update Submitted: 2020-05-13
• Last Update Posted: 2020-05-15
• Primary Completion: 2022-08-14
• Study Completion: 2022-08-14

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 7400000

Inclusion Criteria

• Norwegian citizens aged 45 and above 1.1.1994 - 31.12. 2009 and had stroke events
• Those who attend a cardiovascular health survey who later developed stroke.
• All Norwegians born in the period 1 January 1940 to 31 December 1959 who survived to 1991
• Norwegian citizens aged 45 and above 1.1.2016 and had stroke events

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
R1- Mortality	Mortality follow-up from 1.1.1994 to 31.12.2014	Mortality of Norwegian citizens aged 45 and above 1.1.1994 - 31.12. 2009
R3- Stroke events	Stroke events registered in the Patient registry after 2016, (possibly until 2019)	Norwegian citizens aged 45 and above 1.1.2016
R2- Mortality	Mortality follow-up from 1991-2014.	Mortality of all Norwegians born in the period 1 January 1940 to 31 December 1959 who survived to 1991

Trial Locations

Locations (1)

Department of Community Medicine and Global Health,University of Oslo; 🇳🇴 Oslo, Norway