Ridge Preservation After Tooth Extraction Using Cortical Versus Cancellous Freeze Dried Bone Allograft

Not Applicable

Completed

• Conditions: Tooth Extraction
• Interventions: Device: Cancellous FDBA; Device: cortical FDBA

• Registration Number: NCT01588444
• Lead Sponsor: The University of Texas Health Science Center at San Antonio

Brief Summary

The purpose of this study is to compare cortical and cancellous freeze-dried bone allograft (FDBA) materials in the preservation of alveolar bone following extraction of non-molar teeth. The primary objective is to histologically evaluate and compare the healing of extraction sockets of non-molar teeth grafted with cortical FDBA versus cancellous FDBA for ridge preservation.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-10
• Study First Submitted: 2012-03-16
• Study First Submitted QC: 2012-04-30
• Study First Posted: 2012-05-01
• Primary Completion: 2012-07
• Study Completion: 2012-07
• Results First Submitted: 2014-10-01
• Results First Submitted QC: 2014-10-01
• Results First Posted: 2014-10-06
• Status Verified: 2015-10
• Last Update Submitted: 2015-10-01
• Last Update Posted: 2015-10-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• single rooted tooth requiring extraction with future dental implant placement

Exclusion Criteria

• smoking > 10 cigarettes per day poorly controlled diabetes

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
cancellous FDBA (LifeNet)	Cancellous FDBA	grafting with cancellous mineralized freeze-dried bone allograft (LifeNet Health)
cortical FDBA (LifeNet)	cortical FDBA	CORTICAL FREEZE-DRIED BONE ALLOGRAFT (from LifeNet Health)

Primary Outcome Measures

Name	Time	Method
Histologic Percentage of Vital Bone Formation	18-20 weeks after grafting	Histologic percentage of vital bone formation in bone cores

Trial Locations

Locations (1)

UT Health Science Center Dental School; 🇺🇸 San Antonio, Texas, United States