Gingival Crevicular Fluid Alkaline Phosphatase Activity as a Biomarker of Skeletal Maturation in Comparison to Modified Middle Phalanx of The Middle Finger (MP3) Method in a Sample of Growing Egyptian Females
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 92
- 试验地点
- 1
- 主要终点
- MP3
研究概览
简要总结
Determination of the pubertal growth spurt in Egyptian female patients using gingival crevicular fluid alkaline phosphatase
详细描述
assessment of the pubertal growth spurt in growing Egyptian female patients by using a simple, quick and easy method, through taking a gingival crevicular fluid alkaline phosphatase sample and measuring its concentration. Comparing the concentration of GCF ALP to the standardized middle phalanax of the middle finger MP3 we can predict if it can be an accurate and reliable method as skeletal growth indicator.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 7 Years 至 16 Years（Child）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Gender: only female subjects will be included.
- •Age between 7-16 years old
- •Intermediate or late mixed dentition and permanent dentition
- •Good general health with absence of any nutritional problems or bony disease
- •No usage of any anti-inflammatories or antibiotics in the month preceding the study
- •Fully erupted upper and lower central incisors for sample collection
- •Good gingival and periodontal health as indicated by Probing depth (PD) values that should not exceed 3 mm for the whole dentition.
- •Willingness to participate in the study and sign the informed consent form
排除标准
- •Male adolescent subjects
- •Periodontal and /or gingival disease
- •Systemic and/or bone disease
- •Growth abnormality
结局指标
主要结局
MP3
时间窗: immediately after taking x-rays
periapical x-ray of the middle phalanax of the middle finger
GCF ALP concentration
时间窗: immediately after sample collection
concentration of gingival crevicular fluid alkaline phosphatase
次要结局
未报告次要终点
研究者
sarah samir abdelrahman abelmaged
doctor
Cairo University