Calculator Predicts Early Mortality Post Hepatocellular Carcinoma Resection

Completed

• Conditions: To Predict Early Post-hepatectomy Mortality for HCC

• Registration Number: NCT06621485
• Lead Sponsor: Beijing Tsinghua Chang Gung Hospital

Brief Summary

Using the multicenter data, we developed and validated an individualized online calculator to predict early mortality after liver resection for hepatocellular carcinoma. The user-friendly tool with 6 preoperative predictors demonstrated excellent accuracy. The freely available calculator may help identify high-risk patients and reduce futile liver resection for hepatocellular carcinoma.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-02-15
• Primary Completion: 2024-03-15
• Study Completion: 2024-03-31
• Status Verified: 2024-09
• Study First Submitted: 2024-09-29
• Study First Submitted QC: 2024-09-29
• Last Update Submitted: 2024-09-29
• Study First Posted: 2024-10-01
• Last Update Posted: 2024-10-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 4966

Inclusion Criteria

Adults (age ≥18 years) who underwent curative-intent hepatectomy for newly diagnosed HCC.

HCC diagnosis was confirmed histopathologically.

Exclusion Criteria

Patients undergoing emergency hepatectomy for tumor rupture, as well as individuals with recurrent HCC, and those with missing survival data or less than 90 days of follow-up were excluded.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
90-day death	The period starts from the day of the hepatectomy surgery and extends up to the 90th day post-surgery.	90-day mortality after hepatectomy for HCC

Trial Locations

Locations (1)

Beijing Tsinghua Changgung Hospital; 🇨🇳 Beijing, China