Effectiveness of Rotavirus Immunization at the Community Level in Nicaragua
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Diarrhea
- Sponsor
- Sylvia Becker-Dreps
- Enrollment
- 667
- Status
- Completed
- Last Updated
- 14 years ago
Overview
Brief Summary
The purpose of the investigators study is to compare the rates of childhood diarrhea at the community level before and after the rotavirus vaccination program in León, Nicaragua. From preliminary studies, the investigators anticipate about a 28% reduction in diarrhea following the vaccination program among children who received the vaccine, and a smaller reduction in diarrhea among children who did not receive the vaccine, due to the effects of "herd immunity". In addition, the investigators will collect stool samples from children who develop diarrhea in order determine the etiology of childhood diarrhea in the post-rotavirus immunization era.
Investigators
Sylvia Becker-Dreps
Assistant Professor, Department of Family Medicine
University of North Carolina, Chapel Hill
Eligibility Criteria
Inclusion Criteria
- •Age under 5 years, inclusion in health and demographic surveillance system (CIDS) in Leon, Nicaragua
Exclusion Criteria
- •Parents do not consent to child's participation
Outcomes
Primary Outcomes
Not specified