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临床试验/NCT01133808
NCT01133808已完成不适用

Effectiveness of Rotavirus Immunization at the Community Level in Nicaragua

Sylvia Becker-Dreps0 个研究点目标入组 667 人开始时间: 2010年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
667

研究概览

简要总结

The purpose of the investigators study is to compare the rates of childhood diarrhea at the community level before and after the rotavirus vaccination program in León, Nicaragua. From preliminary studies, the investigators anticipate about a 28% reduction in diarrhea following the vaccination program among children who received the vaccine, and a smaller reduction in diarrhea among children who did not receive the vaccine, due to the effects of "herd immunity". In addition, the investigators will collect stool samples from children who develop diarrhea in order determine the etiology of childhood diarrhea in the post-rotavirus immunization era.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
— 至 5 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Age under 5 years, inclusion in health and demographic surveillance system (CIDS) in Leon, Nicaragua

排除标准

  • Parents do not consent to child's participation

研究者

发起方
Sylvia Becker-Dreps
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Sylvia Becker-Dreps

Assistant Professor, Department of Family Medicine

University of North Carolina, Chapel Hill

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