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Clinical Trials/NCT01133808
NCT01133808
Completed
Not Applicable

Effectiveness of Rotavirus Immunization at the Community Level in Nicaragua

Sylvia Becker-Dreps0 sites667 target enrollmentJanuary 2010
ConditionsDiarrhea

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Diarrhea
Sponsor
Sylvia Becker-Dreps
Enrollment
667
Status
Completed
Last Updated
14 years ago

Overview

Brief Summary

The purpose of the investigators study is to compare the rates of childhood diarrhea at the community level before and after the rotavirus vaccination program in León, Nicaragua. From preliminary studies, the investigators anticipate about a 28% reduction in diarrhea following the vaccination program among children who received the vaccine, and a smaller reduction in diarrhea among children who did not receive the vaccine, due to the effects of "herd immunity". In addition, the investigators will collect stool samples from children who develop diarrhea in order determine the etiology of childhood diarrhea in the post-rotavirus immunization era.

Registry
clinicaltrials.gov
Start Date
January 2010
End Date
January 2011
Last Updated
14 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Sylvia Becker-Dreps
Responsible Party
Sponsor Investigator
Principal Investigator

Sylvia Becker-Dreps

Assistant Professor, Department of Family Medicine

University of North Carolina, Chapel Hill

Eligibility Criteria

Inclusion Criteria

  • Age under 5 years, inclusion in health and demographic surveillance system (CIDS) in Leon, Nicaragua

Exclusion Criteria

  • Parents do not consent to child's participation

Outcomes

Primary Outcomes

Not specified

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