Effectiveness of Rotavirus Immunization at the Community Level in Nicaragua
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 667
研究概览
简要总结
The purpose of the investigators study is to compare the rates of childhood diarrhea at the community level before and after the rotavirus vaccination program in León, Nicaragua. From preliminary studies, the investigators anticipate about a 28% reduction in diarrhea following the vaccination program among children who received the vaccine, and a smaller reduction in diarrhea among children who did not receive the vaccine, due to the effects of "herd immunity". In addition, the investigators will collect stool samples from children who develop diarrhea in order determine the etiology of childhood diarrhea in the post-rotavirus immunization era.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 5 Years(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age under 5 years, inclusion in health and demographic surveillance system (CIDS) in Leon, Nicaragua
排除标准
- •Parents do not consent to child's participation
研究者
Sylvia Becker-Dreps
Assistant Professor, Department of Family Medicine
University of North Carolina, Chapel Hill
