NCT02544230已完成不适用
Efficacy of Granulocyte Transfusions for the Treatment of Severe Infections in Hematological Patients With Febrile Neutropenia
Sorveglianza Epidemiologica Infezioni Fungine Emopatie Maligne1 个研究点 分布在 1 个国家目标入组 101 人开始时间: 2004年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 101
- 试验地点
- 1
- 主要终点
- Infection-related mortality
研究概览
简要总结
The investigators retrospectively evaluated the efficacy of granulocyte transfusions as adjunctive treatment for severe infections in neutropenic fever unresponsive to antimicrobial therapy in hematological patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •presence of absolute neutrophil count <0.5 x 10^9/L
- •evidence of bacterial or fungal infections (including clinical signs of infection, positive cultures or biopsy, and radiological evidences)
- •unresponsiveness to appropriate antimicrobial therapy for at least 48 hours
排除标准
- 未提供
结局指标
主要结局
Infection-related mortality
时间窗: within 30 days after the last granulocyte transfusion
deaths due to infection occurred within 30 days after the last granulocyte transfusion
次要结局
未报告次要终点
研究者
LIVIO PAGANO
Professor
Sorveglianza Epidemiologica Infezioni Fungine Emopatie Maligne
研究点 (1)
Loading locations...
相似试验
已完成
3 期
Granulocyte Transfusion StudyBlood TransfusionInfectionNCT00000581National Heart, Lung, and Blood Institute (NHLBI)
尚未招募
1 期
Study on safety and efficacy of granulocyte transfusion mobilized with G-CSF in related donorSevere neutropenic patients following alloHSCT or chemotherapyJPRN-UMIN000014777Kansai Medical University10
已完成
3 期
To Assess the Efficacy of Granulocyte Colony Stimulating Factor Versus Standard Medical Therapy in Patients of Decompensated CirrhosisCirrhosisNCT02642003Sir Ganga Ram Hospital259
招募中
不适用
Granulocyte colony stimulating factor on fertility rateInfertility.Female infertilityIRCT20160524028038N4Yasouj University of Medical Sciences126
招募中
不适用
Therapeutic effect of granulocyte and monocyte adsorption column (Adacolumn) for refractory skin diseasesInflammatory keratosis (psoriasis vulgaris, psoriasis arthropica), neutrophilic dermatosis (pustular psoriasis, palmoplantar pustulosis, Behcet disease, Sweet disease, gangrene pyoderma, erythema elevatum diutinum) , vasculitis syndrome (nodular arteritis, cutaneous allergic vasculitis, Schonlein-Henoch purpura, Wegener's granulomatosis), eosinophilic disease (hypereosinophilic syndrome, atopic dermatitis), etcJPRN-UMIN000021070Kagoshima University60