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Observational Safety and Effectiveness Study of Adjuvanted Swine Origin A (H1N1) Pandemic Subunit Egg Derived Vaccine

Completed
Conditions
Influenza A (H1N1)
Interventions
Other: This is non-intervention observational study
Registration Number
NCT01101074
Lead Sponsor
Novartis Vaccines
Brief Summary

This observational study will evaluate the safety and effectiveness following administration of adjuvanted Swine Origin A (H1N1) Pandemic Subunit Egg Derived Vaccine through both an ad hoc active monitoring system and a passive surveillance of hospitalization in a large cohort.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
135469
Inclusion Criteria
  • Subjects resident in Emilia-Romagna and either registered with the AUSL of Reggio Emilia, Bologna, Modena and Parma or working in the province of Reggio Emilia, Bologna, Modena and Parma included in the target groups described in the Study Protocol vaccination with H1N1sw vaccine Focetria is recommended - according to the national pandemic plan adopted at the local level - will be eligible for enrolment.
Exclusion Criteria
  • Subjects already vaccinated with another pandemic vaccine or with known contraindications to Focetria, will be excluded from this study.
  • Patients institutionalized in Hospital, Nursing Homes, Rehabilitation Centers, as well as home-cared patients, will also be excluded.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
>60 yearsThis is non-intervention observational study-
6-23 monthsThis is non-intervention observational study-
2-8 yearsThis is non-intervention observational study-
9-17 yearsThis is non-intervention observational study-
18-44 yearsThis is non-intervention observational study-
45-60 yearsThis is non-intervention observational study-
Primary Outcome Measures
NameTimeMethod
Safety of Flu Egg Derived Adjuvanted Swine Origin A(H1N1) Pandemic Subunit Vaccine by estimating the incidence of reported Adverse Events, Serious Adverse Events or Adverse Events of Special Interest in a cohort of actively monitored vaccinated subjectsWithin 3 weeks and 6 weeks after vaccine administration
Secondary Outcome Measures
NameTimeMethod
The occurrence of hospitalization within 6 weeks and 2 years after vaccination in a cohort of subjects vaccinated sw unvaccinated subjects, with Flu Egg Derived Adjuvanted Swine Origin A (H1N1) Pandemic Subunit Vaccine2 years
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