Unani treatment for renal stones

Phase 2

Not yet recruiting

Conditions: Urinary calculus, unspecified,

Registration Number: CTRI/2023/05/052675

Lead Sponsor: NATIONAL INSTITUE OF UNANI MEDICINE

Brief Summary: In the past several decades, especially in developed nations, urolithiasis has become one of the most common disorders of the urinary tract across the globe, with an increase incidence and prevalence in all age groups and genders. According to estimates, at least 10% of people in affluent nations have urolithiasis and the southern part is less affected compared to other parts.

UNANI PERSPECTIVE:

MajÅ«sÄ« in his book kÄmilus sanÄ described that the formation of stone or gravel in urinary tract is due to shadÄ«d harÄrat and Khilt ghalÄ«z. The increased harÄrat tends to dry the moisture of

the khilt ghalÄ«z resulting in the hardening and crystallization of the material leading to stone formation.

According to Jalinoos, renal stone production is caused by two factors. The first cause is Qarah (ulcer) in which the pus is not be evacuated; instead, it collects in the kidney and aids in the creation of calculi. Another cause he mentions is the rÄ«h which gets entrapped in the crevices of the kidney and condenses into hard material i.e. the stone. According to Raziâ€™s concept in the book kitab al Hawi, whenever the kidney, bladder, or joints stone develop, they are composed of lesdÄr mawÄd (a slimy substance) that is acted upon heat. As these substances cannot be excreted, they are deposited in the kidney. Due to heat the material becomes dry and dirty as the moisture gets absorbed and eventually turns it to stone.

Ibn Sina has described that the stones are formed by two causes viz; GhalÄ«z mÄdÄ and retention of this ghalÄ«z mÄdÄ. The mÄdÄ gets transformed into a stone by the innate heat of the kidneys.

In unani system of medicine, the major methods for the treatment of urolithiasis are lithotriptic (Mufattit-i-HasÄt) and diuretic (Mudirr-i-Bawl) medications. These facilitate the easy removal of morbid material i.e; ghalÄ«z mÄdÄ, primarily through the excretory system. Sharbat Aalu Balu is an important unani formulation, being used in urolithiasis. Sharbat Aalu Balu is diuretic and has lithotriptic properties. It also regulates urine output and is nephroprotective in nature.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

Patients with the urinary stones of size less than 10 mm diagnosed by ultrasonography of whole abdomen & pelvis esp.
Both symptomatic & asymptomatic urolithiasis patients.
Only stable cases of urolithiasis will be enlisted.

Exclusion Criteria

Patients having the stone of size more than 10mm 2.
Severe Hydroureteronephrosis 3.
Diabetes mellitus 4.
Patients having any Severe Systemic Disease 5.
Pregnant and lactating Women.
Bladder outlet obstruction.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Size of the renal stone	42 days

Secondary Outcome Measures

Name	Time	Method
1. Pain in abdomen VAS Scale)	2. Burning micturition (Yes/No)

Trial Locations

Locations (1): National Institute of Unani Medicine
🇮🇳
Bangalore, KARNATAKA, India
National Institute of Unani Medicine
🇮🇳Bangalore, KARNATAKA, India
Shaikh Muzaffar Imamsab
Principal investigator
9481302668
shaikhmuzaffar44@gmail.com