NL-OMON50538招募中不适用
Early TUbectomy with delayed oophorectomy to improve quality of life as alternative for risk reducing salpingo-oophorectomy in BRCA1/2 gene mutation carriers - TUBA study
Gynaecologie en Verloskunde0 个研究点目标入组 510 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 510
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64(—)
入选标准
- •- Premenopausal women with a documented BRCA1 and/or BRCA2 germline mutation
- •- Age 25-40 years for BRCA1 mutation carriers, 25-45 years for BRCA2
- •- Childbearing completed
- •- Presence of at least one fallopian tube
- •- Participants may have a personal history of non-ovarian malignancy
排除标准
- •- Postmenopausal status (natural menopause or due to (cancer) treatment)
- •- Wish for second stage RRO within two years after RRS (if clear at enrollment)
- •- Legally incapable
- •- Prior bilateral salpingectomy
- •- A personal history of ovarian, fallopian tube or peritoneal cancer
- •- Evidence of malignant disease at enrollment
- •- Current treatment for malignant disease
- •- Inability to read or speak Dutch
研究者
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