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Prognosis in Patients With Chronic Respiratory Failure Receiving Domiciliary Noninvasive Positive Pressure Ventilation (NPPV)

Completed
Conditions
Chronic Respiratory Failure
Registration Number
NCT00905476
Lead Sponsor
Kyoto University, Graduate School of Medicine
Brief Summary

The purposes of the present study are (1) to analyze baseline patient characteristics cross-sectionally, (2) to analyze the prognosis and its predictive factors, and (3) to examine longitudinal clinical course in patients with chronic respiratory failure receiving domiciliary NPPV.

Detailed Description

Limited data are available about the prognosis and its predictive factors in patients with chronic respiratory failure receiving domiciliary NPPV. In addition, their health status, psychological status and sleep quality seem to be highly disturbed due to severe respiratory insufficiency. Therefore, in the present study, we aim to examine (1) contributive factors to health status based on baseline data, (2) whether patient reported measurements such as health status, dyspnea and psychological status would predict patient's future outcomes, and (3) how they would change for 3 years as compared to physiological measurements.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
56
Inclusion Criteria
  • Patients with chronic respiratory failure receiving domiciliary NPPV for more than 3 months
Exclusion Criteria
  • Uncontrolled severe comorbidities
  • Patients with tracheotomy.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Prognosis/Mortality3 years
Secondary Outcome Measures
NameTimeMethod
Psychological statusAt entry and every year for 3 years
Pulmonary functionAt entry and every year for 3 years
Arterial blood gasAt entry and every year for 3 years
DyspneaAt entry and every year for 3 years
Health statusAt entry and every year for 3 years
6 minute walking testsAt entry and every year for 3 years
Sleep qualityAt entry and every year for 3 years

Trial Locations

Locations (11)

Kobe City Hospital Organization Medical Center West Hospital

🇯🇵

Kobe, Japan

NHO Minami-Kyoto Hospital

🇯🇵

Joyo, Japan

Komaki Municipal Hospital

🇯🇵

Komaki, Japan

Graduate School of Medicine, Kyoto University

🇯🇵

Kyoto, Japan

Kobe City Medical Center General Hospital

🇯🇵

Kobe, Japan

Ogaki Municipal Hospital

🇯🇵

Ogaki, Japan

Otsu Red Cross Hospital

🇯🇵

Otsu, Japan

Tosei General Hospital

🇯🇵

Seto, Japan

Takatsuki Red Cross Hospital

🇯🇵

Takatsuki, Japan

NHO Toneyama National Hospital

🇯🇵

Toyonaka, Japan

Tenri Hospital

🇯🇵

Tenri, Japan

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