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临床试验/NCT01469741
NCT01469741已完成不适用

Rehabilitation of Everyday Memory Impairment in Parkinson Disease: A Pilot Study

Washington University School of Medicine2 个研究点 分布在 1 个国家目标入组 74 人开始时间: 2011年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
74
试验地点
2

研究概览

简要总结

Cognitive impairment is common among non-demented individuals with Parkinson disease (PD) and is a significant source of disability and reduced quality of life. Unfortunately, there are no successful interventions to address these impairments. Prospective memory impairment is a particularly functionally- and clinically-relevant problem in PD. The investigator's project will determine if a targeted intervention strategy improves PD participants' prospective memory. The investigator's goal is to improve PD patients' everyday prospective memory so they can successfully perform desired activities and roles.

详细描述

Cognitive impairment is common among non-demented individuals with Parkinson disease (PD) and is a significant source of disability and reduced quality of life. Unfortunately, there are no successful interventions to address these impairments. Prospective memory impairment is a particularly functionally- and clinically-relevant problem in PD. The investigator's project will determine if a targeted intervention strategy improves PD participants' prospective memory. The investigator will use a randomized controlled design and a laboratory-based assessment of prospective memory to test the effect of the strategy in a controlled environment. The investigator will also see if PD participants, with support from an occupational therapist (OT), can generalize the strategy to their complex, real-world environments and tasks. Our goal is to improve PD patients' everyday prospective memory so they can successfully perform desired activities and roles.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Supportive Care
盲法
Single (Participant)

入排标准

年龄范围
50 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Participants will be males and females over age 50 who meet criteria for idiopathic typical PD, are Hoehn & Yahr39 stage I-III (mild-moderate disease) and are treated with levodopa/carbidopa.

排除标准

  • Possible dementia,
  • treatment with certain medications that interfere with cognition (e.g., anticholinergics),
  • change in medications over the study period, other neurological disorders, brain surgery (e.g., STN DBS),
  • history of psychotic disorder or significant current psychiatric disorder, or any condition that would interfere with testing (e.g., vision problems).

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Erin Foster

Assistant Professor of Occupational Therapy, Neurology and Psychiatry

Washington University School of Medicine

研究点 (2)

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