A Pilot Study Using Transcranial Magnetic Stimulation (TMS) to Investigate the Role of the Temporal Cortex in Schizophrenic Patients With Auditory Hallucinations

The University of New South Wales1 site in 1 country18 target enrollmentSeptember 1999

ConditionsAuditory Hallucinations

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: Auditory Hallucinations
Sponsor: The University of New South Wales
Enrollment: 18
Locations: 1
Primary Endpoint: Daily Voices Ratings (Mental Health Research Institute, Victoria)
Status: Completed
Last Updated: 16 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Transcranial magnetic stimulation (TMS) involves the use of magnetic fields to non-invasively stimulate the brain. Studies overseas have suggested this may be an effective and safe treatment for auditory hallucinations in patients with schizophrenia. This is a sham-controlled, double-blind trial of TMS stimulation for the treatment of auditory hallucinations in patients with schizophrenia.

Registry

clinicaltrials.gov

Start Date

September 1999

End Date

September 2008

Last Updated

16 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

The University of New South Wales

Eligibility Criteria

Inclusion Criteria

•Over 18, with DSM-IV diagnosis of Schizophrenia and auditory hallucinations of clear external origins, refractory to pharmacotherapy and occurring at least 5 times per day.

Exclusion Criteria

•Subjects with contraindications to TMS (e.g. epilepsy, pacemaker) or those with an unacceptably high risk (e.g. suicide risk) will be excluded from the study.