Transcranial Magnetic Stimulation (TMS) for Treatment of Auditory Hallucinations

Phase 1

Completed

• Conditions: Auditory Hallucinations
• Interventions: Device: Transcranial magnetic stimulation; Device: Sham

• Registration Number: NCT00763841
• Lead Sponsor: The University of New South Wales

Brief Summary

Transcranial magnetic stimulation (TMS) involves the use of magnetic fields to non-invasively stimulate the brain. Studies overseas have suggested this may be an effective and safe treatment for auditory hallucinations in patients with schizophrenia. This is a sham-controlled, double-blind trial of TMS stimulation for the treatment of auditory hallucinations in patients with schizophrenia.

Detailed Description

Not available

Study Timeline

• Study Start: 1999-09
• Primary Completion: 2008-09
• Study Completion: 2008-09
• Study First Submitted: 2008-09-30
• Study First Submitted QC: 2008-09-30
• Study First Posted: 2008-10-01
• Status Verified: 2009-11
• Last Update Submitted: 2010-01-19
• Last Update Posted: 2010-01-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

• Over 18, with DSM-IV diagnosis of Schizophrenia and auditory hallucinations of clear external origins, refractory to pharmacotherapy and occurring at least 5 times per day.

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Exclusion Criteria

• Subjects with contraindications to TMS (e.g. epilepsy, pacemaker) or those with an unacceptably high risk (e.g. suicide risk) will be excluded from the study.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
1	Transcranial magnetic stimulation	Stimulation will be given daily at a particular site for three days a week
2	Sham	-

Primary Outcome Measures

Name	Time	Method
Daily Voices Ratings (Mental Health Research Institute, Victoria)	Daily

Trial Locations

Locations (1)

School of Psychiatry; 🇦🇺 Sydney, New South Wales, Australia