A Pilot Study Using Transcranial Magnetic Stimulation (TMS) to Investigate the Role of the Temporal Cortex in Schizophrenic Patients With Auditory Hallucinations

The University of New South Wales2 个研究点分布在 1 个国家目标入组 18 人开始时间: 1999年9月最近更新: 2010年1月20日

适应症

试验速览

阶段: 1 期
状态: 已完成
发起方: The University of New South Wales
入组人数: 18
试验地点: 2
主要终点: Daily Voices Ratings (Mental Health Research Institute, Victoria)

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Transcranial magnetic stimulation (TMS) involves the use of magnetic fields to non-invasively stimulate the brain. Studies overseas have suggested this may be an effective and safe treatment for auditory hallucinations in patients with schizophrenia. This is a sham-controlled, double-blind trial of TMS stimulation for the treatment of auditory hallucinations in patients with schizophrenia.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Crossover
主要目的: Treatment
盲法: Double (Participant, Outcomes Assessor)

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Over 18, with DSM-IV diagnosis of Schizophrenia and auditory hallucinations of clear external origins, refractory to pharmacotherapy and occurring at least 5 times per day.

排除标准

•Subjects with contraindications to TMS (e.g. epilepsy, pacemaker) or those with an unacceptably high risk (e.g. suicide risk) will be excluded from the study.

结局指标

主要结局

Daily Voices Ratings (Mental Health Research Institute, Victoria)

时间窗: Daily

次要结局

未报告次要终点

研究者

发起方

The University of New South Wales

申办方类型

Other

研究点 (2)

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