NCT00763841已完成1 期
A Pilot Study Using Transcranial Magnetic Stimulation (TMS) to Investigate the Role of the Temporal Cortex in Schizophrenic Patients With Auditory Hallucinations
适应症
干预措施
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Daily Voices Ratings (Mental Health Research Institute, Victoria)
研究概览
简要总结
Transcranial magnetic stimulation (TMS) involves the use of magnetic fields to non-invasively stimulate the brain. Studies overseas have suggested this may be an effective and safe treatment for auditory hallucinations in patients with schizophrenia. This is a sham-controlled, double-blind trial of TMS stimulation for the treatment of auditory hallucinations in patients with schizophrenia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Over 18, with DSM-IV diagnosis of Schizophrenia and auditory hallucinations of clear external origins, refractory to pharmacotherapy and occurring at least 5 times per day.
排除标准
- •Subjects with contraindications to TMS (e.g. epilepsy, pacemaker) or those with an unacceptably high risk (e.g. suicide risk) will be excluded from the study.
研究组 & 干预措施
1
Experimental
Stimulation will be given daily at a particular site for three days a week
干预措施: Transcranial magnetic stimulation (Device)
2
Sham Comparator
干预措施: Sham (Device)
结局指标
主要结局
Daily Voices Ratings (Mental Health Research Institute, Victoria)
时间窗: Daily
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
已完成
1 期
Preliminary Study of Transcranial Magnetic Stimulation for Stroke RehabilitationCerebrovascular AccidentNCT00050128National Institute of Neurological Disorders and Stroke (NINDS)15
Enrolling By Invitation
不适用
TMS - Intracranial ElectrodesEpilepsy IntractableNCT03702127Aaron Boes50
已完成
不适用
TMS vs Conventional Therapy for the Treatment of Functional Neurological Non Epileptic Seizure DisorderPsychogenic Non-Epileptic SeizureNCT05241366El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez28
暂停
不适用
Magnetic Brain Stimulation in the Treatment of Mild Cognitive ImpairmentMild Cognitive ImpairmentNCT02420522University of Manitoba64
撤回
1 期
Roflumilast TMS-EEG PlasticitySynaptic PlasticityNCT04369547University of Calgary