Effects of tumeric and Serrapeptase gel on reducing pain and improve range of motion in patients with osteoarthritis of the knee

Phase 3

Recruiting

• Conditions: Osteoarthritis of knee; osteoarthritis.

• Registration Number: IRCT20140804018677N7
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 April 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

age>45y and having knee osteoarthritis according to American College of Rheumatology diagnostic criteria
Knee pain with at least three of the followings: age>50, morning stiffness<30 min, crepitation, bone tenderness at knee, knee bone enlargement, warmness or pain in addition to osteophyte according to radiography
Grade 2 or 3 of osteoarthritis according to Kellgren and Lawrence system
Pain intensity between 5-8 at baseline according to VAS
Able to walk independently

Exclusion Criteria

having joint arteritis, orthopedic or severe cardiovascular diseases
having intra-articular injection of corticosteroids in past 3 months, as well as gel, and Platelet-rich plasma (PRP) in past year
having allergic reaction to tumeric and Serrapeptase

Study & Design

• Study Type: interventional
• Study Design: Not specified