Comparison of Adductor canal block with local infiltration analgesia for post-operative pain management in total knee arthroplasty
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Primary Objective:
研究概览
简要总结
TITLE OF THESIS: Adductor Canal Block versus Local Infiltration Anelgesia & Wound infiltration for Post-operative pain management in Total Knee Arthroplasty.
INTRODUCTION:Total knee arthroplasty (TKA), although a reliable and common surgical procedure to relieve pain and restore function, is associated with moderate to severe postoperative pain which can contribute to delayed rehabilitation. Reports suggest that short-term effective anaesthesia and analgesia can have long-lasting beneficial effects on recovery from surgery.
The available interventions and management strategies for reducing and managing post – op pain after TKA include: Pre-emptive analgesia, local infiltration (Intraoperative peri-articular and extra-articular), systemic analgesics, neuraxial analgesia (Continuous epidural analgesia) and regional nerve blocks- single shot or continuous.
LIA has been demonstrated to be equivalent to epidural anaesthesia with respect to postoperative analgesia, but superior in terms of improved mobilisation.
Saphenous nerve block in the adductor canal (ACB) has been found to be equally effective as FNB with an advantage of selective sensory blockade and hence better ambulatory distance with lesser incidence of falls.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA I and II patients of either sex
- •Age between 18-75 years.
- •Weight between 55 -100 kg.
排除标准
- •Patients with mental dysfunction or cognitive deficiency.
- •Patients with neuro-muscular, vestibular, hepatic or major systemic disease.
- •History of psychiatric illness
- •History of alcohol or drug abuse
- •History of allergy to local anaesthetic
- •Medical conditions affecting balance and coordination
- •Patient who is not giving consent.
- •Neuropathies associated with disease condition, lesion, drugs etc.
结局指标
主要结局
Primary Objective:
时间窗: Time to 1st perception of pain (NRS3)
Pain relief assessment as
时间窗: Time to 1st perception of pain (NRS3)
measuredd by
时间窗: Time to 1st perception of pain (NRS3)
- Numerical Rating Scale (NRS) score changes
时间窗: Time to 1st perception of pain (NRS3)
次要结局
- Secondary Objective:(Time to 1st rescue analgesic requirement (NRS3))