Prospective Observational Study to Determine the Utility of REMS in Comparison to NEWS2 for Predicting Morbidity and Mortality Among Patients Presenting to the ED Suspicion of Sepsis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 130
- 试验地点
- 1
- 主要终点
- To determine the utility of REMS score over NEWS2 score - number of days of intensive care.
研究概览
简要总结
Prospective observational study to determine the utility of Rapid Emergency Medicine Score (REMS) in comparison to National Early Warning Score2 (NEWS2) for predicting morbidity and mortality among patients presenting to the Emergency Department with clinical suspicion of Sepsis
详细描述
Rapid Emergency Medicine Score (REMS) is an attenuated version of the Acute Physiology and Chronic Health Evaluation (APACHE) II score and has utility in predicting mortality in non- surgical patients. The NEWS2 can be used on all hospitalized patients to allow for the early detection of clinical deterioration and potential need for higher level of care. NEWS2 is closely associated with sepsis, however REMS is not so. But in recent studies comparing other EWS (Early Warning Scores) of sepsis, REMS was found to be superior.
Hence comparing REMs against NEWS2 to determine prognostication value of both scores in sepsis.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients presenting to ED of Tertiary Care Hospital in Thrissur.
- •Patients age >/=18 years
- •Patients who give informed consent for participation in the study.
- •Suspicion of sepsis at the time of presentation to ED as per SSC Guidelines 2021
排除标准
- •All patients with an alternate diagnosis other than sepsis at the time of discharge.
- •Patients referred from other hospitals with diagnosis of sepsis, after initiation of treatment
研究组 & 干预措施
Sepsis patients
干预措施: Antibiotics, Vasopressors (Drug)
结局指标
主要结局
To determine the utility of REMS score over NEWS2 score - number of days of intensive care.
时间窗: 18 months
To compare REMS score against NEWS2 score with regard to morbidity indicators as - Number of days of intensive care
To determine the utility of REMS score over NEWS2 score - need for vasopressor administration
时间窗: 18 months
To compare REMS score against NEWS2 score with regard to morbidity indicators as - need for vasopressor administration
To determine the utility of REMS score over NEWS2 score - number of days spent as IP
时间窗: 18 months
To compare REMS score against NEWS2 score with regard to morbidity indicators as - number of days spent in hospital
To determine the utility of REMS score over NEWS2 score - need for mechanical ventilation
时间窗: 18 months
To compare REMS score against NEWS2 score with regard to morbidity indicators as - need for mechanical ventilation
次要结局
- To determine in- hospital mortality of patients with clinical suspicion of sepsis(30 days)
- To determine the utility of REMS score over NEWS2 score of patients admitted with qSOFA >/=2(18 months)
研究者
Dr Reshma Haridas
Junior Resident
Jubilee Mission Medical College and Research Institute