NCT03540940已完成不适用
The Effect of Positive End-expiratory Pressure During Induction of General Anesthesia on Atelectasis Formation and Non-hypoxic Apnea Time in Small Children: a Randomized Controlled Trials
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 4
- 主要终点
- Duration of Apnea
研究概览
简要总结
Positive end-expiratory pressure (PEEP) applied during induction of anesthesia prevents atelectasis formation and increases the duration of nonhypoxic apnea in obese and nonobese patients. PEEP also prevents atelectasis formation in pediatric patients. Because pediatric patients arterial desaturation during induction of anesthesia develops rapidly, we studied the clinical benefit of PEEP applied during anesthesia induction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 1 Month 至 2 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •pediatric patients undergoing general anesthesia using endotracheal intubation
排除标准
- •previous history of lung disease
- •anticipated difficulty in airway management
研究组 & 干预措施
zero positive end expiratory pressure
Experimental
干预措施: ZEEP (Other)
Positive end expiratory pressure
Experimental
干预措施: PEEP (Other)
结局指标
主要结局
Duration of Apnea
时间窗: from the start of apnea until SpO2 reached 95%, maximum 5 minutes.
次要结局
未报告次要终点
研究者
Hee-Soo Kim
professor
Seoul National University Hospital
研究点 (4)
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