Evaluation of Apelin-13 and Apelin-36 in Women With Recurrent Pregnancy Loss

Completed

• Conditions: Recurrent Pregnancy Loss
• Interventions: Diagnostic Test: Apelin-13, Apelin-36

• Registration Number: NCT05205044
• Lead Sponsor: Ain Shams University

Brief Summary

Lower Apelin levels are associated with hypertensive disorders with pregnancy, yet no studies investigated its levels in recurrent pregnancy loss

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-01-11
• Study First Submitted QC: 2022-01-11
• Study Start: 2022-01-23
• Study First Posted: 2022-01-24
• Primary Completion: 2023-01-30
• Study Completion: 2023-01-30
• Status Verified: 2023-02
• Last Update Submitted: 2023-02-12
• Last Update Posted: 2023-02-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 88

Inclusion Criteria

• pregnant women in first trimester
• negative antiphospholipid markers
• normal karyotype

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Exclusion Criteria

• multiple pregnancy
• fetal malformations
• maternal diseases
• smoking or alcohol use
• history of or risk factors for preterm labor

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Recurrent pregnancy loss	Apelin-13, Apelin-36	-
Healthy	Apelin-13, Apelin-36	-

Primary Outcome Measures

Name	Time	Method
Apelin-13 and Apelin-36	1 year	Serum levels of Apelin-13 and Apelin-36

Trial Locations

Locations (2)

AinShams Maternity Hospital; 🇪🇬 Cairo, Egypt

Ain Shams University Maternity Hospital; 🇪🇬 Cairo, Cairo/القاهرة, Egypt