Comparison of two methods of administration of deferoxamine (intravenous and subcutaneous) in terms of impact on reducing iron overload in thalassemia patients who have suffered heart failure.
Phase 2
- Conditions
- Iron overload..Abnormal level of blood mineral.
- Registration Number
- IRCT201206289827N2
- Lead Sponsor
- Kermanshah University of Medical Sciences and Health Services
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
suffering major Thalassemia and cardiac ejection fraction less than 50%.
Exclusion criteria: inflammatory disease; anemia and liver disorders.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum ferritin. Timepoint: 1 week after intervention (desferal administration). Method of measurement: Use of ELISA method, unit will be mg/L.
- Secondary Outcome Measures
Name Time Method Cardiac Ejection Fraction. Timepoint: 2 weeks after intervention. Method of measurement: Using Ecocardiography, the unit will be percent.