Effect of acupuncture on survival benefit and attenuating muscle atrophy in patients with sepsis-induced myopathy - a prospective cohort study

Department of Intensive Care Unit, the First Affiliated Hospital of Guangzhou University of Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

试验速览

暂无简介。

•1. Aged 18 to 85 years old;
•2. Meet the criteria of Sepsis-320which define sepsis as infection + SOFA >=2 points within the first 24 hour;
•3. The first time admitted to ICU and expect to survive within the first 48 hours;
•4. Informed consent signed by the patient or immediate family member (next to kin);
•5. The Rectus Femoris cross-sectional area (RFcsa) decreased more than 9.24%21 after ICU admission;
•6. Survival within ICU stay.

•1. A confirmed positive result of pregnancy or urine beta-HCG test;
•2. The questionnaire(MRC-SS/FIM/consent form) could not be completed due to cognitive abnormalities;
•3. A newly diagnosed primary neuromuscular disease when admitted to the hospital;
•4. Patients who have leg amputationpelvic/femoral fractures or knee/hip replacement that could not complete the measure of RFcsa;
•5. Malnutrition (BMI less than 18.5 kg/m2) or cachexia;
•6. Patients with metastatic tumors (PD) or ongoing chemotherapy;
•7. Patients with cardiorespiratory arrest or imminent death
•8. Patients with long-term corticoid treatment;
•9. Can't walk independently before sepsis onset;
•10. ICU length of stay <7 days;
•11.Sepsis has been onset more than 5 days before ICU admission;
•12. Therapy withdrawal and consent refusal.

发起方

Department of Intensive Care Unit, the First Affiliated Hospital of Guangzhou University of Chinese Medicine