The Role of High Velocity Nasal Insufflation in Prevention of Respiratory Complications in Severe Chest Trauma
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 86
- 主要终点
- Incidence of atelectasis in chest trauma patients
研究概览
简要总结
to compare the respiratory complications in patient managed with high velocity nasal insufflation versus patients managed with conventional low flow oxygen in patients with severe chest trauma
详细描述
- Chest trauma are associated with significant morbidity and mortality due to respiratory failure and pneumonia.
- The two main goals of therapy are pain management and pulmonary care and support. There is strong evidence for providing good analgesia to facilitate volume expansion treatment and chest physiotherapy, aiming for deep breathing and effective cough to reduce secretions and prevent the atelectasis.
- Oxygen supplementation is often included as supportive therapy added to bundles of care for patients of chest trauma with rib fractures.
High -velocity nasal insufflation (HVNI ) was first developed for neonates and has gained increasing use in adult patients for prevention and treatment of respiratory failure. High-flow humidified oxygen with flow rates from 30 to100 L/min with high fraction of inspired oxygen( FiO2) is able to be delivered. Positive end-expiratory pressure can be generated, preventing alveoli collapse. The washout of carbon dioxide (CO2)and replacement with enriched O2 purportedly decreases work of breathing and increases breathing effectiveness.
- Routine tests for chest injuries include chest X-rays and computed tomography (CT) scans. Ultrasound has the advantages of being inexpensive, readily available and being free of ionizing radiation .
- In thoracic trauma cases, ultrasonography of the lungs is valuable for evaluating various chest diseases, including chest wall haematoma and fractures, pleural cavity involvement with pleural effusion, haemothorax, and pneumothorax. The ultrasound can also assess the reduce in lung aeration by changing the lung surface and generating distinct patterns as in pulmonary contusions and compression atelectasis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 55 Years(Child, Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Chest trauma patients with lung injury confirmed by ct imaging
- •the age from 15-55 years old
- •No indication of mechanical ventilation at the time of admission to the intensive care unit
排除标准
- •• Patients < 15years old
- •requiring endotracheal intubation and mechanical ventilation immediately on admission for any cause
- •facial fractures or base of skull fractures
- •Who did not receive a chest computed tomography (CT) scan
- •Glasgow Coma Scale <10
- •Massive surgical emphysema
- •COPD Patients ( chronic obstructive pulmonary disease )
结局指标
主要结局
Incidence of atelectasis in chest trauma patients
时间窗: 3 years
Incidence of atelectasis in chest trauma patients using the chest ultrasound measured by lung consolidation score.
次要结局
- respiratory complications,hospital stay and Comfort levels(3 years)
研究者
Mohamed Yasser Abdelgaber
Mohamed yasser
Assiut University
