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The availability study of tissue oxygenation monitor in pharyngeal and tracheal mucosa

Phase 2
Recruiting
Conditions
Cancer or severe aspiration condition requiring total laryngectomy
Registration Number
JPRN-jRCTs042220151
Lead Sponsor
Mukaigawa Takashi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
20
Inclusion Criteria

1. Patients scheduled for palliative or radical surgery for total laryngectomy*
2. If due to cancer, the primary site is irrelevant
3. If due to cancer, any tissue type
4. Patients who gave written informed consent before enrollment
5. Aged 18 or older at the time of obtaining consent

* Including total laryngectomy to prevent aspiration due to severe aspiration

Exclusion Criteria

1. Patients who cannot be closed with pharyngeal mucosal suture alone and will require a free flap
2.Uncontrolled diabetes mellitus
3. Unstable angina pectoris (angina pectoris with onset or exacerbation within the last 3 weeks) or history of myocardial infarction within 6 months.
4.Poorly controlled hypertension as a complication.
5.Receiving continuous systemic (oral or intravenous) steroids or other immunosuppressants
6. SPO2<90% at enrollment
7. Severe occlusive vasculopathy
8. Complications with other cancers requiring simultaneous surgery
9.In addition, patients who are considered inappropriate as subjects of this study by the judgment of the doctor

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Comprehensive determination of the presence or absence of acquisition values of tissue oxygen saturation of normal mucosa away from the wound.
Secondary Outcome Measures
NameTimeMethod
1.Results of using Tokkale<br>2.Presence or absence of suture failure<br>3.Presence or absence of tracheal necrosis<br>4.Presence or absence of preoperative irradiation
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