An open randomized controlled clinical study of efficacy of vasadi dashang ghan vati in the management of urdhwag amlapitta
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Decrease in symptoms of urdhwag amlapitta
研究概览
简要总结
Gastro oesophageal reflux Disease (GERD) is typically managed using medications like H2 blockers
and Proton Pump Inhibitors (PPI). However, these drugs primarily offer symptomatic relief and can
lead to patient dependency. Short-term use of PPI may result in side effects such as headaches,
rashes, dizziness, and various gastrointestinal issues like nausea, abdominal pain, flatulence,
constipation, and diarrhoea and PPI long term use causes side effects like iron deficiency
anaemia. Therefore, there is a growing need for an alternative drug that effectively manages
Amlapitta (GERD) with fewer side effects.
Currently, Ayurveda is gaining popularity because many Ayurveda medicines are herbal preparations
with minimal or no harmful side effects. This has sparked interest in exploring Ayurveda alternatives
that can alleviate the signs and symptoms of Urdhwag Amlapitta (GERD) in comparison to the
modern drug Omeprazole. Out of many medicines described in samhita for the treatment of Urdhwag
amlapitta vasadi dashang kwath has been stated to be useful in Amlapitta .
So this research is to study vasadi dashang kwatha in the form of Ghan vati .Ghan vati has less
particle size as compare to kwatha kalpana, also easy handling makes it convenient for patient. Also,
comparing efficacy of ghan vati in urdhwag Amlapitta with modern drug Omeprazole. As we know
modern drug has its own side effects so there is need for its alternative in ayurveda.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- All
入选标准
- •1.All sex 2.Age 18-80 years 3.Patients presenting with Lakshanas of amlapitta.
排除标准
- •1.Pregnant and lactating women.
- •2.Participant those are k/c/o chronic alcohol addiction 3.Not willing for trial or non-cooperative patients 4.Patients those are k/c/o HIV, HbsAg 5.Patients who are on steroid, non-steroid anti-inflammatory drugs.
结局指标
主要结局
Decrease in symptoms of urdhwag amlapitta
时间窗: 21 days
次要结局
- 1. Avipak (Indigestion)(2. Klama (tiredness))
研究者
Vaishali Shivlal Deshmukh
APMs Ayurved Mahavidyalaya Sion Mumbai
