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临床试验/CTRI/2024/10/075604
CTRI/2024/10/075604尚未招募4 期

An open randomized controlled clinical study of efficacy of vasadi dashang ghan vati in the management of urdhwag amlapitta

Vaishali Shivlal Deshmukh1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年11月1日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
Decrease in symptoms of urdhwag amlapitta

研究概览

简要总结

Gastro oesophageal reflux Disease (GERD) is typically managed using medications like H2 blockers

and Proton Pump Inhibitors (PPI). However, these drugs primarily offer symptomatic relief and can

lead to patient dependency. Short-term use of PPI may result in side effects such as headaches,

rashes, dizziness, and various gastrointestinal issues like nausea, abdominal pain, flatulence,

constipation, and diarrhoea and PPI long term use causes side effects like iron deficiency

anaemia. Therefore, there is a growing need for an alternative drug that effectively manages

Amlapitta (GERD) with fewer side effects.

Currently, Ayurveda is gaining popularity because many Ayurveda medicines are herbal preparations

with minimal or no harmful side effects. This has sparked interest in exploring Ayurveda alternatives

that can alleviate the signs and symptoms of Urdhwag Amlapitta (GERD) in comparison to the

modern drug Omeprazole. Out of many medicines described in samhita for the treatment of Urdhwag

amlapitta vasadi dashang kwath has been stated to be useful in Amlapitta .

So this research is to study vasadi dashang kwatha in the form of Ghan vati .Ghan vati has less

particle size as compare to kwatha kalpana, also easy handling makes it convenient for patient. Also,

comparing efficacy of ghan vati in urdhwag Amlapitta with modern drug Omeprazole. As we know

modern drug has its own side effects so there is need for its alternative in ayurveda.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • 1.All sex 2.Age 18-80 years 3.Patients presenting with Lakshanas of amlapitta.

排除标准

  • 1.Pregnant and lactating women.
  • 2.Participant those are k/c/o chronic alcohol addiction 3.Not willing for trial or non-cooperative patients 4.Patients those are k/c/o HIV, HbsAg 5.Patients who are on steroid, non-steroid anti-inflammatory drugs.

结局指标

主要结局

Decrease in symptoms of urdhwag amlapitta

时间窗: 21 days

次要结局

  • 1. Avipak (Indigestion)(2. Klama (tiredness))

研究者

发起方
Vaishali Shivlal Deshmukh
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Vaishali Shivlal Deshmukh

APMs Ayurved Mahavidyalaya Sion Mumbai

研究点 (1)

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