A Single Arm Open Label Clinical Trial To Evaluate The Efficacy Of Combined Therapy - Brahmyadi Syrup With Shirodhara And Shiropichu In The Management Of Attention-Deficit/Hyperactivity Disorder

Modern ADHD treatment have significant drawback including the potential to have a serious negative influence on a child’s entire development. Ayurveda is holding numerous ways to diagnose and manage various diseases. Although several studies have been conducted and some remain are on-going on this disease but still any specific precise management and strategy not have been established, thus much more research must be done in order to achieve this goal in future. Due to their low socioeconomic level many parents in developing nations like India unable to afford the different therapies required for ADHD. Therefore, careful research is needed to discover more affordable, accessible and palatable medications for such disease. BrahmyadiYoga is mentioned in BhaisajyaRatnavali text book, Unmadrogaadhikaar Chapter Number 24 as a *Unmadaharayog.*Till now, as per scholars’ knowledge there is no research work available on this drug for ADHD in children. It contains drugs like Brahmi, Vacha, Shankhpushpi, Kushmaand, Kustha which are considered as Medhya (~nootropic) drugs according to Acharya Priyavart Sharma.Active ingredients of these drugs acts on brain function which may also be beneficial in improving the symptoms of ADHD. Also, these drugs are easily available and cost effective. To improve the palatability and compliance of drug, Brahmyadiyoga will be modified as a Syrup form. Bacosides active ingredients of Brahmi responsible for improving memory related disorders, and enhance efficiency of transmission of nerve impulse there by strengthening memory and cognition.Shankhpushpi has a calming effect by regulating the body’s production of the stress hormones, adrenaline and cortisol. The bioactive components of Convolvulus pluricaulis are Sitosterol glycoside, octacosanoltetracosane, hydroxycinnamic acid, and glucose. These metabolites contribute to its nootropic and memory enhancing properties, along with its other pharmacological activities. Rhizome of Vacha has been reported to possess tranquilizing, neuroprotective, anti-cholinesterase, anticonvulsant activity.Certain research works done on Kushmanda have yielded beneficial effects on mental health. Kushmanda considers best for promotion of longevity, promotion of memory and intellect Kustha have Hypotensive and vaso relaxation effect, CNS depressant effect, immune-modulator.

Shirodhara is a method whereby pouring any liquid or medicated liquid(milk/oil/buttermilk)  over the forehead of the patient in the form of a regular stream from a particular height (precisely 3.14 inches (as mentioned in Dharakalpa of Sahasrayogam) in the form of oscillatory movements for 30-45 minutes. Mind and higher consciousness is affected in disease like ADHD. And these can be considered under broad term Unmada in Ayurveda. For providing an tranquilizing effect and increasing attention, Shirodhara is the well-known treatment modality. Shiropichu is procedure of applying the oil to the vertex using cotton pad impregnated with oil. It is found to be more beneficial in neuropsychiatric disorders. Because of its easy applicability along with added effect of all Moordhinitaila these considred as important procedure in ADHD.