Hybrid Imaging Modalities for the Evaluation of Infection

Not Applicable

Completed

• Conditions: Infectious Diseases

• Registration Number: NCT00230152
• Lead Sponsor: Rambam Health Care Campus

Brief Summary

The synergistic value of the fusion of physiologic and anatomical data has been described using several co-registration techniques for various nuclear medicine procedures and morphologic imaging modalities (single photon emission computed tomography-computed tomography \[SPECT-CT\], SPECT-magnetic resonance imaging \[MRI\], camera-based positron emission tomography \[PET\]-CT and PET-CT). The researchers hypothesize that fusion of nuclear medicine (NM) and CT data acquired sequentially in a single imaging session on one device is clinically superior to side-by-side evaluation of separately performed imaging tests. They hypothesize that more accurate localization of increased radiotracer activity on NM procedures will improve the diagnostic accuracy for detection of infection and will subsequently have a significant impact on patient management.

The purpose of the present study is to assess the clinical value of this new technology of fused imaging in patients undergoing diagnostic nuclear medicine evaluation for suspicion of an infection process.

Detailed Description

The researchers hypothesize that fusion of nuclear medicine (NM) and CT data acquired sequentially in a single imaging session on one device is clinically superior to side-by-side evaluation of separately performed imaging tests. They hypothesize that more accurate localization of increased radiotracer activity on NM procedures will improve the diagnostic accuracy for detection of infection and will subsequently have a significant impact on patient management.

The purpose of the present study is to assess the clinical value of this new technology of fused imaging in patients undergoing diagnostic nuclear medicine evaluation for suspicion of an infection process.

Study Timeline

• Status Verified: 2005-09
• Study First Submitted: 2005-09-29
• Study First Submitted QC: 2005-09-29
• Study First Posted: 2005-09-30
• Study Start: 2006-02
• Primary Completion: 2007-04
• Study Completion: 2009-03
• Last Update Submitted: 2010-10-21
• Last Update Posted: 2010-10-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Patients referred for NM imaging procedures to assess the presence of infectious processes.
• Patients signed informed consent

Exclusion Criteria

• The study will not be performed in pregnant or lactating women.
• Patients unable or unwilling to tolerate the scan until its completion

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
The impact of the imaging modality on patient management	3 years

Secondary Outcome Measures

Name	Time	Method
The impact of the imaging modality on patient management	2 years

Trial Locations

Locations (1)

Rambam Medical Center; 🇮🇱 Haifa, Israel