To evaluate the healing outcome with human amniotic membrane, hydroxyapatite graft and laser biostimulation in patients having periapical lesion.

Phase 2

• Conditions: Health Condition 1: K049- Other and unspecified diseases ofpulp and periapical tissues

• Registration Number: CTRI/2024/05/067868
• Lead Sponsor: ITS Dental College Hospital And Reseach Centre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.18 to 40 years of age

2.Teeth with Periapical Radiolucency indicated for surgery.

3.Patient not on any medication affecting periapical healing. (Corticosteroids, chemotherapeutic agents, Anticoagulants, drugs which reduce osteoclastic activity.)

4.Noncontributory medical history (ASA I & II).

5.Single rooted anterior teeth with intact palatal/lingual bone.

6.Lesion size less than 10 mm.

Exclusion Criteria

1.Pregnant females

2.Patient with periodontally compromised teeth.

3.Patient having insufficient motivation to report back for follow ups.

5.Lesion size greater than 10 mm.

6.Vertical root fracture

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate and compare periapical healing after endodontic surgeries using Human Amniotic Membrane, hydroxyapatite graft and Laser Biostimulation using CBCT. <br/ ><br> <br/ ><br>Timepoint: Periapical healing will be evaluated at the time interval of baseline,3 months, 6 months and 12 months interval.

Secondary Outcome Measures

Name	Time	Method
To find out which group among human amniotic membrane, hydroxyapatite graft And laser biostimulation will give the best healing outcome after endodontic surgeries.Timepoint: At the baseline, 3 months, 6 months And 12 months interval.