Acupuncture for Unexplained Subfertiliy
- Conditions
- Unexplained Infertility
- Interventions
- Other: AcupunctureOther: expectant management
- Registration Number
- NCT02624076
- Lead Sponsor
- Heilongjiang University of Chinese Medicine
- Brief Summary
Infertility affects one in six couples. In a quarter of them, routine tests of semen quality, ovulation or tubal patency fail to reveal any abnormalities and the cause of infertility is unexplained. Acupuncture is being increasingly used by couples with all types of infertility and initial trials have suggested that it could be potentially beneficial in some cases. A number of systematic reviews of acupuncture in IVF have shown conflicting results, but there is no evidence to inform best practice in unexplained infertility. In addition, as an intervention, acupuncture is not cost neutral as it involves multiple visits for treatment sessions delivered by a skilled practitioner. Thus, while acupuncture could have the potential to increase live birth rates in women with unexplained infertility, the clinical and cost effectiveness of acupuncture needs to be confirmed in the context of a large randomized controlled trial.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 1423
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Acupuncture plus expectant management expectant management - Acupuncture plus expectant management Acupuncture - expectant management expectant management -
- Primary Outcome Measures
Name Time Method live birth rate Up to 4 months
- Secondary Outcome Measures
Name Time Method Miscarriage rate Up to 14 months quality of life Up to 14 months pregnancy rate Up to 14 months Other pregnancy complications such as early pregnancy loss, gestational diabetes mellitus, pregnancy-induced hypertension and birth of small-for-gestational-age (SGA) babies. Up to 14 months Side effect Up to 14 months
Trial Locations
- Locations (16)
Wenzhou Chinese Medicine Hospital
🇨🇳Wenzhou, Zhejiang, China
First Affiliated Hospital of Hunan University of Chinese
🇨🇳Changsha, Hunan, China
Maternal and Child Health Hospital of Xuzhou
🇨🇳Xuzhou, Jiangsu, China
First Affiliated Hospital of Tianjin University of Chinese Medicine
🇨🇳Tianjin, Tianjin, China
Hangzhou Chinese Medicine Hospital
🇨🇳Hangzhou, China
Guangzhou Medical School First Affiliated Hospital
🇨🇳Guangzhou, Guangdong, China
Daqing Longnan hospital
🇨🇳Daqing, Heilongjiang, China
The Daqing Oilfield General Hospital
🇨🇳Daqing, Heilongjiang, China
Obstetrics and Gynecology,Heilongjiang University of Chinese Medicine
🇨🇳Harbin, Heilongjiang, China
Daqing Oilfield General Hospital
🇨🇳Daqing, Heilongjiang, China
Department of Obstetrics and Gynecology,First Affliated Hospital,Heilongjiang University of Chinese Medicine .
🇨🇳Harbin, Heilongjiang, China
Jiangxi University of Chinese Medicine Affiliated Hospital
🇨🇳Nanchang, Jiangxi, China
First Hospital, Jiangxi college of Chinese Medicine
🇨🇳Nanchang, Jiangxi, China
Shanxi Chinese Medicine Hospital
🇨🇳Shangxi, Shanxi, China
Shanxi Hospital of Chinese Medicine
🇨🇳Taiyuan, Shanxi, China
Tianjin Tanggu Maternity and Child Care Center
🇨🇳Tianjin, Tianjin, China