imited neck dissection versus full neck dissection - in limited nodal metastasis in mouth cancers - which is better
Phase 2
- Conditions
- Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynxHealth Condition 2: C068- Malignant neoplasm of overlappingsites of other and unspecified parts of mouth
- Registration Number
- CTRI/2022/11/047490
- Lead Sponsor
- Max Group of healthcare
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients with age >=18 with histologically proven squamous cell carcinoma of the oral cavity with clinicoradiological evidence of node, that is cN+ , with no clinical or radiological evidence of extranodal extension( ENE) will be included in the study.
2.Patients with nodal staging N1, N2a and N2b will be included in the study.
Exclusion Criteria
1.Patients with previous history of radiation or surgery will not be included in the study.
2.Patients with nodes at level IV or level V will not be included in the study.
3.Patients with nodal involvement at multiple levels, that is - more than 2 will not be included in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the 2 year disease specific survival (DSS) and 2 years overall survival (OS) in patients undergoing selective neck dissection (level I- IV) versus patients undergoing comprehensive neck dissection ( level I â?? V) in clinicoradiologically N+ necks in oral cavity squamous cell carcinoma.Timepoint: To assess the 2 year disease specific survival (DSS) and 2 years overall survival (OS) in patients undergoing selective neck dissection (level I- IV) versus patients undergoing comprehensive neck dissection ( level I â?? V) in clinicoradiologically N+ necks in oral cavity squamous cell carcinoma.
- Secondary Outcome Measures
Name Time Method To assess the involvement of level V lymph nodes in all the patients undergoing a comprehensive neck dissection in oral cavity carcinoma.Timepoint: Histopathology report after surgery - 15 days